Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  17
• Reference
  J:4113 Snoek M, et al., Three Hsp70 genes are located in the C4-H-2D region: possible candidates for the Orch-1 locus [published erratum appears in Genomics 1993 Aug;17(2):533]. Genomics. 1993 Feb;15(2):350-6
• ID
  MGI:46707

Genes

Gene	Assay Type	Description
Neu1	overlapping clones	cosmid 7
Hspa1b	overlapping clones	cosmid 7, cosmid 4
Hspa1a	overlapping clones	cosmid 4, cosmid 33
Orch1	resistance/susceptibility
Hspa1l	overlapping clones	cosmid 33, cosmid 11
Lsm2	overlapping clones	cosmid 33, cosmid 11
Vars1	overlapping clones	cosmid 11, cosmid 19, cosmid 32

Notes

• Reference
  Authors use G9 and G7b for locus symbols Bat7 and D17H6S56E-2 respectively. G7a/Bat6/G7 is represented by symbol D17H6S56E.
• Experiment
  The screening of a cosmid library from C57BL/Rij resulted in the isolation of overlapping cosmids within the H2 region of mouse Chromosome 17. These overlapping clones enabled the physical order of loci within the Hsp70 cluster as follows: Neu1 - Hspa1b - Hspa1a - Hspa1l - Lsm2 - Vars2. As estimated from text fig. 1 this genomic distance includes approximately 90kb of DNA. Additional analysis of a number of mouse strains with recombinant H2 haplotypes provided information that the mouse Orch1 locus is confined to a 60kb region including the genes Hspa1b - Hspa1a - Hspa1l - Lsm2 - Vars2.