Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  18
• Reference
  J:1701 Justice MJ, et al., A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18. Genomics. 1992 Aug;13(4):1281-8
• ID
  MGI:40807

Genes

Gene	Assay Type	Description
Hc18	Southern analysis	pMR196
Kif5b	Southern analysis	pXPE
Map3k8	Southern analysis	pTP2
Ttr	Southern analysis	pHH64
Hk1-rs1	Southern analysis	rHK-1
Apc	Southern analysis	MAPC 73-1A
D18Leh1	reported elsewhere
Fgf1	reported elsewhere
Nr3c1	reported elsewhere
Mcc	Southern analysis	MCC-MB56-1
Lmnb1	Southern analysis	77-553
Pdgfrb	Southern analysis	Pdgfrb cDNA
Csf1r	reported elsewhere
Cd74	reported elsewhere
D18Fcr2	Southern analysis	748-7
Camk2a	Southern analysis	pk2a3
D18Leh2	reported elsewhere
Emb-rs3	Southern analysis	p17P
Grp	Southern analysis	pB12
Gnal	Southern analysis	rga
Mtv38	reported elsewhere
Dcc	Southern analysis	pDCC 1.65
D18Fcr1	Southern analysis	pAB7
Mbp	reported elsewhere

Notes

• Reference
  Revised gene symbols: Ttr, Hk1-rs1, Fgf-1 (formerly Palb, Hk-1rs1 and Fgfa, respectively).
  
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Kif5b	Ttr	Apc	Fgf1	Nr3c1	Mcc	Lmnb1	Pdgfrb	D18Fcr2	Emb-rs3	Grp	Gnal	Mtv38	Dcc	D18Fcr1	Mbp
18	b	b	b	b	b	b	b	b	b	b	b	b	b	b	b	b
12	s	s	s	s	s	s	s	s	s	s	s	s	s	s	s	s
2	s	b	b	b	b	b	b	b	b	b	b	b	b	b	b	b
2	b	s	s	s	s	s	s	s	s	s	s	s	s	s	s	s
2	s	s	b	b	b	b	b	b	b	b	b	b	b	b	b	b
5	b	b	s	s	s	s	s	s	s	s	s	s	s	s	s	s
1	s	s	s	b	b	b	b	b	b	b	b	b	b	b	b	b
2	b	b	b	s	s	s	s	s	s	s	s	s	s	s	s	s
0	s	s	s	s	b	b	b	b	b	b	b	b	b	b	b	b
1	b	b	b	b	s	s	s	s	s	s	s	s	s	s	s	s
1	s	s	s	s	s	b	b	b	b	b	b	b	b	b	b	b
1	b	b	b	b	b	s	s	s	s	s	s	s	s	s	s	s
2	s	s	s	s	s	s	b	b	b	b	b	b	b	b	b	b
1	b	b	b	b	b	b	s	s	s	s	s	s	s	s	s	s
1	s	s	s	s	s	s	s	b	b	b	b	b	b	b	b	b
1	b	b	b	b	b	b	b	s	s	s	s	s	s	s	s	s
2	s	s	s	s	s	s	s	s	b	b	b	b	b	b	b	b
0	b	b	b	b	b	b	b	b	s	s	s	s	s	s	s	s
1	s	s	s	s	s	s	s	s	s	b	b	b	b	b	b	b
1	b	b	b	b	b	b	b	b	b	s	s	s	s	s	s	s
1	s	s	s	s	s	s	s	s	s	s	b	b	b	b	b	b
1	b	b	b	b	b	b	b	b	b	b	s	s	s	s	s	s
0	s	s	s	s	s	s	s	s	s	s	s	b	b	b	b	b
1	b	b	b	b	b	b	b	b	b	b	b	s	s	s	s	s
0	s	s	s	s	s	s	s	s	s	s	s	s	b	b	b	b
1	b	b	b	b	b	b	b	b	b	b	b	b	s	s	s	s
1	s	s	s	s	s	s	s	s	s	s	s	s	s	b	b	b
1	b	b	b	b	b	b	b	b	b	b	b	b	b	s	s	s
1	s	s	s	s	s	s	s	s	s	s	s	s	s	s	b	b
0	b	b	b	b	b	b	b	b	b	b	b	b	b	b	s	s
1	s	s	s	s	s	s	s	s	s	s	s	s	s	s	s	b
4	b	b	b	b	b	b	b	b	b	b	b	b	b	b	b	s

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Hc18	Ttr	3	93
Ttr	Map3k8	7	89
Map3k8	Fgf1	5	118
Fgf1	Hk1-rs1	1	120
Hk1-rs1	Mcc	2	109
Mcc	D18Leh1	11	90
D18Leh1	Pdgfrb	1	104
Pdgfrb	D18Fcr2	4	120
D18Fcr2	Emb-rs3	3	111
Emb-rs3	Grp	0	79
Grp	Gnal	1	85
Gnal	Mtv38	1	124
Mtv38	Dcc	1	107
Dcc	D18Fcr1	0	42
D18Fcr1	Mbp	5	53
Hc18	Map3k8	0	189
Map3k8	D18Leh1	0	25
Pdgfrb	Cd74	0	192
Pdgfrb	Csf1r	0	175
D18Fcr2	Camk2a	0	94
D18Fcr2	D18Leh2	0	49
Hc18	Hc18	0	142
Ttr	Hk1-rs1	2	30
Hk1-rs1	Map3k8	1	31

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Kif5b	Ttr	4	68	5.882	2.853
Ttr	Apc	7	68	10.294	3.685
Apc	Fgf1	3	68	4.412	2.490
Fgf1	Nr3c1	1	68	1.471	1.460
Nr3c1	Mcc	2	68	2.941	2.049
Mcc	Lmnb1	3	68	4.412	2.490
Lmnb1	Pdgfrb	2	68	2.941	2.049
Pdgfrb	D18Fcr2	6	192	3.125	1.256
D18Fcr2	Emb-rs3	5	182	2.747	1.212
Emb-rs3	Grp	2	147	1.361	0.955
Grp	Gnal	2	154	1.299	0.912
Gnal	Mtv38	2	193	1.036	0.729
Mtv38	Dcc	3	176	1.705	0.976
Dcc	D18Fcr1	1	110	0.909	0.905
D18Fcr1	Mbp	10	126	7.937	2.408