Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  6
• Reference
  J:11037 Norman DJ, et al., Genetic mapping of the lurcher locus on mouse chromosome 6 using an intersubspecific backcross. Genomics. 1991 Jan;9(1):147-53
• ID
  MGI:39977

Genes

Gene	Allele	Assay Type	Description
Cpa1		Southern analysis	11-3
Npy		Southern analysis	clone Npy-5
Cbl-ps1		Southern analysis	418 bp EcoRI-PstI fragment
Grid2	Grid2^Lc	visible phenotype
Igk		Southern analysis	clone pJk
Fabp1		Southern analysis	rat cDNA
Itpr1		Southern analysis	PCD6035 oligo

Notes

• Reference
  This article reports a multipoint backcross typed for all loci in 97 mice and additional mice typed for only some of the loci. These additional mice appear as 2-point data.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  F1 direction known.
  

CROSS

• Type
  Backcross, sexes unspecified or combined
• Female Parent
  <c> <c> <c> <c> <c> <c> <c>/<b> <b> <b> <b> <b> <b> <b>
• Strain
  (M. m. castaneus x B6CBA-A/A Grid2)F1-Grid2
• Male Parent
  <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b>
• Strain
  B6CB-A/A
• Allele 1
  b from M. m. castaneus
• Allele 2
  c from (C57BL/6 x CBA)F1

CROSS Data

MC #mice	Cpa1	Npy	Cbl-ps1	Grid2	Igk	Fabp1	Itpr1
31	c	c	c	c	c	c	c
34	b	b	b	b	b	b	b
7	b	c	c	c	c	c	c
4	c	b	b	b	b	b	b
4	b	b	c	c	c	c	c
0	c	c	b	b	b	b	b
1	b	b	b	b	c	c	c
1	c	c	c	c	b	b	b
7	b	b	b	b	b	b	c
8	c	c	c	c	c	c	b

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Cpa1	Npy	0	1
Npy	Cbl-ps1	11	260
Cbl-ps1	Grid2	2	296
Grid2	Igk	4	189
Igk	Fabp1	0	3
Fabp1	Itpr1	1	1

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Cpa1	Npy	11	98	11.224	3.189
Npy	Cbl-ps1	15	368	4.076	1.031
Cbl-ps1	Grid2	2	395	0.506	0.357
Grid2	Igk	6	290	2.069	0.836
Igk	Fabp1	0	100	0.000	0.000
Fabp1	Itpr1	16	99	16.162	3.700