About   Help   FAQ
Igk Complex/Cluster/Region Detail
Summary
  • Symbol
    Igk
  • Name
    immunoglobulin kappa chain complex
  • Synonyms
    kappa
Location &
Maps
more
  • Sequence Map
    Chr6:67532620-70703738 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 30.89 cM, cytoband F1-pter
  • Mapping Data
    44 experiments
Strain
Comparison
more
  • SNPs within 2kb
    99669 from dbSNP Build 142
  • PCR
    1
  • RFLP
    3
Human Diseases
less
  • Mutations/Alleles
    4 with disease annotations
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 3 alleles in 3 genetic backgrounds
    68 phenotypes from multigenic genotypes
    189 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit abnormal B cell number and differentiation.
Expression
less
  • Other Mouse Links
    GEO
Sequences &
Gene Models
less
  • All Sequences
    4
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 243469 NCBI Gene Model | MGI Sequence Detail 3171119 C57BL/6J ±  kb
transcript AJ880391 GenBank | ENA | DDBJ | MGI Sequence Detail 333 Not Specified  
polypeptide Q5F2I7 UniProt | EBI | MGI Sequence Detail 111 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR050150 Immunoglobulin Variable Light Chain
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less
  • All nucleic 11
    Genomic 6
    cDNA 2
    Primer pair 1
    Other 2
Other
Accession IDs
less
MGD-MRK-11292
References
more
  • Summaries
    All 316
    Diseases 3
    Phenotypes 189
  • Earliest
    J:6050 Hengartner H, et al., Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4494-8
  • Latest
    J:365238 Cohen AA, et al., Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals. Cell. 2024 Oct 3;187(20):5554-5571.e19
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory