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Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    9
  • Reference
    J:109029 Mulligan MK, et al., Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6368-73
  • ID
    MGI:3639673
Genes
Notes
  • Experiment
    Candidate genes for alcohol consumption loci were screened using microarray analysis. A panel of 107 microarrays were screened using mRNA from 3 inbred strains and 6 coisogenic strains with known differences in alcohol consumption. A large set of identified genes were further refined by analyzing mRNA from a congenic line carrying DBA/2J-derived DNA from 9 cM - 58 cM on a C57BL/6J genetic background.

    Candidate genes Pknox2, Scn4b, 9030425E11Rik, and 111003A03Rik coincide with Etohc3, an alcohol consumption QTL at 29 cM (chr9).

    Other candidate genes in the chromosome 9 congenic interval identified by microarray analysis included Arhgef12, Acad11 (formerly 5730439E10Rik) Carm1, Cryab, Cox5a, Dlat, Fxyd6, Limd1, Nicn1, Nmnat3, Rbp1, Sc5d, Tcf12, Vps11, and Zfp291.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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