About   Help   FAQ
Phenotype Images associated with this Gene
Symbol
Name
ID
Rho
rhodopsin
MGI:97914


17 phenotype image(s) for Rho alleles
Showing image(s) 1 to 10
Show   figures per page Next Last

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

Caption: Severe retinal degeneration in Rhotm2.1Kpal/Rhotm2.1Kpal Gnat1tm1Clma/Gnat1tm1Clma mice and less severe degeneration in Rhotm2.1Kpal/Rhotm2.1Kpal Lrattm1Kpal/Lrattm1Kpal mice (details)
Represented Alleles:
Gnat1tm1Clma, G protein subunit alpha transducin 1; targeted mutation 1, C L Makino
Lrattm1Kpal, lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase); targeted mutation 1, Krzysztof Palczewski
Rhotm2.1Kpal, rhodopsin; targeted mutation 2.1, Krzysztof Palczewski
Copyright: This image is from Zhang N, J Clin Invest 2013 Jan 2;123(1):121-37 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194158
Caption: Progressive retinal degeneration in heterozygous and homozygous Rhotm2.1Kpal mice (details)
Represented Alleles:
Rhotm2.1Kpal, rhodopsin; targeted mutation 2.1, Krzysztof Palczewski
Copyright: This image is from Zhang N, J Clin Invest 2013 Jan 2;123(1):121-37 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194158
Caption: Retinal abnormalities in heterozygous and homozygous Rhotm2.1Kpal mice (details)
Represented Alleles:
Rhotm2.1Kpal, rhodopsin; targeted mutation 2.1, Krzysztof Palczewski
Copyright: This image is from Zhang N, J Clin Invest 2013 Jan 2;123(1):121-37 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194158
Caption: Rhodopsin mislocalization, fundus autofluorescent spots, and Muller/macrophage/microglial cell activation in retinas of Rhotm2.1Kpal/Rhotm2.1Kpal mice (details)
Represented Alleles:
Rhotm2.1Kpal, rhodopsin; targeted mutation 2.1, Krzysztof Palczewski
Copyright: This image is from Zhang N, J Clin Invest 2013 Jan 2;123(1):121-37 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194158
Caption: Reduced thickness of rod photoreceptor cell layers in Rhotm2.1Kpal/Rhotm2.1Kpal retina (details)
Represented Alleles:
Rhotm2.1Kpal, rhodopsin; targeted mutation 2.1, Krzysztof Palczewski
Copyright: This image is from Zhang N, J Clin Invest 2013 Jan 2;123(1):121-37 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194158
Caption: Rod reprogramming prevents retinal degeneration in tamoxifen treated Rhotm1Jlem/Rhotm1Jlem Nrltm1Jcco/Nrltm1Jcco Tg(CAG-cre/Esr1*)5Amc/0 mice (details)
Represented Alleles:
Nrltm1Jcco, neural retina leucine zipper gene; targeted mutation 1, Joseph C Corbo
Rhotm1Jlem, rhodopsin; targeted mutation 1, Janis Lem
Tg(CAG-cre/Esr1*)5Amc, transgene insertion 5, Andrew P McMahon
Copyright: This image is from Montana CL, Proc Natl Acad Sci U S A 2013 Jan 29;110(5):1732-7. Copyright 2013 National Academy of Sciences, U.S.A. J:193697
Caption: Outer nuclear layer of the retina is preserved in tamoxifen treated Rhotm1Jlem/Rhotm1Jlem Nrltm1Jcco/Nrltm1Jcco Tg(CAG-cre/Esr1*)5Amc/0 mice (details)
Represented Alleles:
Nrltm1Jcco, neural retina leucine zipper gene; targeted mutation 1, Joseph C Corbo
Rhotm1Jlem, rhodopsin; targeted mutation 1, Janis Lem
Tg(CAG-cre/Esr1*)5Amc, transgene insertion 5, Andrew P McMahon
Copyright: This image is from Montana CL, Proc Natl Acad Sci U S A 2013 Jan 29;110(5):1732-7. Copyright 2013 National Academy of Sciences, U.S.A. J:193697
Caption: Effect of genetic depletion of 11-cis-retinal production (Lrattm1Kpal/Lrattm1Kpal) on retinal degeneration in Rhotm1.1Kpal/Rho+ mice (details)
Represented Alleles:
Lrattm1Kpal, lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase); targeted mutation 1, Krzysztof Palczewski
Rhotm1.1Kpal, rhodopsin; targeted mutation 1.1, Krzysztof Palczewski
Rpe65450L, retinal pigment epithelium 65; 450 Leucine
Rpe65450M, retinal pigment epithelium 65; 450 Methionine
Copyright: This image is from Sakami S, J Biol Chem 2011 Mar 25;286(12):10551-67 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:170648
Caption: Retinal degeneration in Rhotm1.1Kpal/Rho+ and Rhotm1.1Kpal/Rhotm1.1Kpal mice (details)
Represented Alleles:
Rhotm1.1Kpal, rhodopsin; targeted mutation 1.1, Krzysztof Palczewski
Copyright: This image is from Sakami S, J Biol Chem 2011 Mar 25;286(12):10551-67 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:170648
Caption: Rods and cones in Rhotm1.1Kpal/Rho+ mice (details)
Represented Alleles:
Rhotm1.1Kpal, rhodopsin; targeted mutation 1.1, Krzysztof Palczewski
Copyright: This image is from Sakami S, J Biol Chem 2011 Mar 25;286(12):10551-67 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:170648

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory