Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Myl2
myosin, light polypeptide 2, regulatory, cardiac, slow
MGI:97272

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Click on allele symbol for full phenotype details.

	Caption: Autophagosome accumulation in Mfn2^tm1.1Mzhe/Mfn2^tm1.1Mzhe Myl2^tm1(cre)Krc/Myl2⁺ hearts (details) Represented Alleles: Mfn2^tm1.1Mzhe, mitofusin 2; targeted mutation 1.1, Ming Zheng Myl2^tm1(cre)Krc, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien Copyright: This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865
	Caption: Impaired lipid metabolism and accumulation of lipofuscin granules in Mfn2^tm1.1Mzhe/Mfn2^tm1.1Mzhe Myl2^tm1(cre)Krc/Myl2⁺ cardiomyocytes (details) Represented Alleles: Mfn2^tm1.1Mzhe, mitofusin 2; targeted mutation 1.1, Ming Zheng Myl2^tm1(cre)Krc, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien Copyright: This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865
	Caption: Mfn2^tm1.1Mzhe/Mfn2^tm1.1Mzhe Myl2^tm1(cre)Krc/Myl2⁺ cardiomyocytes show a greater loss of mitochondrial membrane potential following ischemia-reperfusion (details) Represented Alleles: Mfn2^tm1.1Mzhe, mitofusin 2; targeted mutation 1.1, Ming Zheng Myl2^tm1(cre)Krc, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien Copyright: This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865
	Caption: Enlarged mitochondria in Mfn2^tm1.1Mzhe/Mfn2^tm1.1Mzhe Myl2^tm1(cre)Krc/Myl2⁺ heart (details) Represented Alleles: Mfn2^tm1.1Mzhe, mitofusin 2; targeted mutation 1.1, Ming Zheng Myl2^tm1(cre)Krc, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien Copyright: This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865
	Caption: Dilated cardiomyopathy in Myl2^tm2.1Chen/Myl2^tm2.1Chen mice (details) Represented Alleles: Myl2^tm2.1Chen, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 2.1, Ju Chen Copyright: This image is from Sheikh F, J Clin Invest 2012 Apr 2;122(4):1209-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184548
	Caption: Sarcomeres from Myl2^tm2.1Chen/Myl2^tm2.1Chen mice show Z-line thickening at 6 months of age (details) Represented Alleles: Myl2^tm2.1Chen, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 2.1, Ju Chen Copyright: This image is from Sheikh F, J Clin Invest 2012 Apr 2;122(4):1209-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184548
	Caption: Cardiac calcification and fibrosis in Myl2^tm2.1Chen/Myl2^tm2.1Chen mice (details) Represented Alleles: Myl2^tm2.1Chen, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 2.1, Ju Chen Copyright: This image is from Sheikh F, J Clin Invest 2012 Apr 2;122(4):1209-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184548
	Caption: Abnormal cardiac structure in Tg(Myh6-Myl2)21Rbns/0 mice (details) Represented Alleles:* Tg(Myh6-Myl2)21Rbns, transgene insertion 21, Jeffrey Robbins Copyright:* This image is from Sanbe A, J Biol Chem 1999 Jul 23;274(30):21085-94 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:114298
	Caption: Abnormal cardiomyocytes in Tg(Myh6-Myl2)21Rbns/0 mice (details) Represented Alleles:* Tg(Myh6-Myl2)21Rbns, transgene insertion 21, Jeffrey Robbins Copyright:* This image is from Sanbe A, J Biol Chem 1999 Jul 23;274(30):21085-94 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:114298

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