Symbol Name ID

Hmgcl 3-hydroxy-3-methylglutaryl-Coenzyme A lyase MGI:96158

2 phenotype image(s) for Hmgcl alleles Showing image(s) 1 to 2

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Caption: The leucine metabolite 2-ketoisocaproate induces liver steatosis in Hmgcltm2Gam/Hmgcltm2Gam Speer6-ps1Tg(Alb-cre)21Mgn/0 mice (details) Represented Alleles: Hmgcltm2Gam, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase; targeted mutation 2, Grant A Mitchell Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson Copyright: This image is from Gauthier N, PLoS One 2013;8(7):e60581, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:204294

Caption: Abnormalities of mitochondrial ultrastructure in Hmgcltm2Gam/Hmgcltm2Gam Speer6-ps1Tg(Alb-cre)21Mgn/0 hepatocytes (details) Represented Alleles: Hmgcltm2Gam, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase; targeted mutation 2, Grant A Mitchell Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson Copyright: This image is from Gauthier N, PLoS One 2013;8(7):e60581, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:204294