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Symbol Name ID |
Rprd2
regulation of nuclear pre-mRNA domain containing 2 MGI:1922387 |
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Caption: Rprd2em1(IMPC)J/Rprd2em1(IMPC)J embryos are developmentally delayed, show impaired embryo turning, abnormal head shape, caudal neural tube kinks and incomplete cranial neural tube closure, abnormal heart morphology and abnormal yolk sacs.
(details)
Represented Alleles:
Rprd2em1(IMPC)J,
regulation of nuclear pre-mRNA domain containing 2; endonuclease-mediated mutation 1, Jackson
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Caption: Placental abnormalities in Rprd2em1(IMPC)J/Rprd2em1(IMPC)J (-/-) embryos include diminished spongiotrophoblast layer, abnormal chorioallantoic interface, impaired chorioallantoic branching, and multiple labyrinth zone defects.
(details)
Represented Alleles:
Rprd2em1(IMPC)J,
regulation of nuclear pre-mRNA domain containing 2; endonuclease-mediated mutation 1, Jackson
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Caption: E8.5 Rprd2em1(IMPC)J/Rprd2em1(IMPC)J embryos are slightly delayed but display typical germ layer patterning.
(details)
Represented Alleles:
Rprd2em1(IMPC)J,
regulation of nuclear pre-mRNA domain containing 2; endonuclease-mediated mutation 1, Jackson
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Caption: E9.5 Rprd2em1(IMPC)J/Rprd2em1(IMPC)J embryos are delayed yet they maintain appropriate expression of key markers in all 3 germ lineages.
(details)
Represented Alleles:
Rprd2em1(IMPC)J,
regulation of nuclear pre-mRNA domain containing 2; endonuclease-mediated mutation 1, Jackson
Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu.
J:374598
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/30/2025 MGI 6.24 |
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