Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
MGI:104878

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	Caption: Prkar1a heterozygosity accelerates osteosarcoma development in Tg(Bglap2-TAg)1Rkho/0 mice (details) Represented Alleles: Prkar1a^tm1.2Lsk, protein kinase, cAMP dependent regulatory, type I, alpha; targeted mutation 1.2, Lawrence Kirschner Tg(Bglap2-TAg)1Rkho, transgene insertion 1, Rama Khokha Tg(Col1a1-cre)1Kry, transgene insertion 1, Gerard Karsenty Copyright: This image is from Molyneux SD, J Clin Invest 2010 Sep 1;120(9):3310-25 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:165282
	Caption: Bone tumorigenesis nd abundant osteoclasts in Prkar1a^tm1.2Lsk/Prkar1a⁺ Tg(Col1a1-cre)1Kry/0 mice (details) Represented Alleles: Prkar1a^tm1.2Lsk, protein kinase, cAMP dependent regulatory, type I, alpha; targeted mutation 1.2, Lawrence Kirschner Tg(Col1a1-cre)1Kry, transgene insertion 1, Gerard Karsenty Copyright: This image is from Molyneux SD, J Clin Invest 2010 Sep 1;120(9):3310-25 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:165282
	Caption: Osteosarcoma characterization in Tg(Bglap2-TAg)1Rkho/0 and Prkar1a^tm1.2Lsk/Prkar1a⁺ Tg(Col1a1-cre)1Kry/0 Tg(Bglap2-TAg)1Rkho/0 mice (details) Represented Alleles: Prkar1a^tm1.2Lsk, protein kinase, cAMP dependent regulatory, type I, alpha; targeted mutation 1.2, Lawrence Kirschner Tg(Bglap2-TAg)1Rkho, transgene insertion 1, Rama Khokha Tg(Col1a1-cre)1Kry, transgene insertion 1, Gerard Karsenty Copyright: This image is from Molyneux SD, J Clin Invest 2010 Sep 1;120(9):3310-25 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:165282
	Caption: Dexamethasone suppression has no effect on Prkar1a^tm1Lsk/Prkar1a^tm1Lsk Tg(Akr1b7-cre)1Anm/0 adrenals (details) Represented Alleles: Prkar1a^tm1Lsk, protein kinase, cAMP dependent regulatory, type I, alpha; targeted mutation 1, Lawrence S Kirschner Tg(Akr1b7-cre)1Anm, transgene insertion 1, Antoine Martinez Copyright: This image is from Sahut-Barnola I, PLoS Genet 2010;6(6):e1000980, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:161521
	Caption: Morphological defects and progressive hyperplasia in Prkar1a^tm1Lsk/Prkar1a^tm1Lsk Tg(Akr1b7-cre)1Anm/0 adrenals (details) Represented Alleles: Prkar1a^tm1Lsk, protein kinase, cAMP dependent regulatory, type I, alpha; targeted mutation 1, Lawrence S Kirschner Tg(Akr1b7-cre)1Anm, transgene insertion 1, Antoine Martinez Copyright: This image is from Sahut-Barnola I, PLoS Genet 2010;6(6):e1000980, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:161521
	Caption: Tumors in Prkar1a^tm1Gsm/Prkar1a⁺ mice (details) Represented Alleles: Prkar1a^tm1Gsm, protein kinase, cAMP dependent regulatory, type I, alpha; targeted mutation 1, G Stanley McKnight Copyright: This image is from Veugelers M, Proc Natl Acad Sci U S A 2004 Sep 28;101(39):14222-7. Copyright 2004 National Academy of Sciences, U.S.A. J:93393
	Caption: Prkar1a^tm1Gsm/Prkar1a^tm1Gsm embryos are severely growth-retarded (details) Represented Alleles: Prkar1a^tm1Gsm, protein kinase, cAMP dependent regulatory, type I, alpha; targeted mutation 1, G Stanley McKnight Copyright: This image is from Amieux PS, J Biol Chem 2002 Jul 26;277(30):27294-304 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:78010
	Caption: Prkar1a^tm1Gsm/Prkar1a^tm1Gsm embryos have deficiencies in cranial and trunk mesenchyme (details) Represented Alleles: Prkar1a^tm1Gsm, protein kinase, cAMP dependent regulatory, type I, alpha; targeted mutation 1, G Stanley McKnight Copyright: This image is from Amieux PS, J Biol Chem 2002 Jul 26;277(30):27294-304 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:78010
	Caption: Prkar1a^tm1Gsm/Prkar1a^tm1Gsm embryos exhibit aberrant migration of mesodermal cells from the primitive streak at E6.5 (details) Represented Alleles: Prkar1a^tm1Gsm, protein kinase, cAMP dependent regulatory, type I, alpha; targeted mutation 1, G Stanley McKnight Copyright: This image is from Amieux PS, J Biol Chem 2002 Jul 26;277(30):27294-304 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:78010

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