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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ehbp1em1(IMPC)J
Name: EH domain binding protein 1; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:6342439
Synonyms: Ehbp1-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Ehbp1em1(IMPC)J/Ehbp1em1(IMPC)J embryos are often smaller, are incompletely turned, have abnormal heads, and most have caudal neural tube kinks, abnormally shaped hearts, branchial arch defects, and misshapen tail tip. Some have incomplete cranial neural tube closure and pale yolk sacs.Ehbp1em1(IMPC)J/Ehbp1em1(IMPC)JC57BL/6NJ-Ehbp1em1(IMPC)J/Mmjax
At E9.5, Ehbp1em1(IMPC)J/Ehbp1em1(IMPC)J placentas are properly developed.Ehbp1em1(IMPC)J/Ehbp1em1(IMPC)JC57BL/6NJ-Ehbp1em1(IMPC)J/Mmjax
E8.5 Ehbp1em1(IMPC)J/Ehbp1em1(IMPC)J embryos are small and dysmorphic although they have all 3 germ layers.Ehbp1em1(IMPC)J/Ehbp1em1(IMPC)JC57BL/6NJ-Ehbp1em1(IMPC)J/Mmjax
E9.5 Ehbp1em1(IMPC)J/Ehbp1em1(IMPC)J embryos exhibit appropriate germ layer patterning but abnormal embryo turning in which the embryo is contorted by the unturned tail.Ehbp1em1(IMPC)J/Ehbp1em1(IMPC)JC57BL/6NJ-Ehbp1em1(IMPC)J/Mmjax
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/09/2025
MGI 6.24 		The Jackson Laboratory