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Phenotype Images associated with this Allele
Nomenclature
Symbol: Kctd5em1(IMPC)J
Name: potassium channel tetramerisation domain containing 5; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:6283649
Synonyms: Kctd5-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Kctd5em1(IMPC)J/Kctd5em1(IMPC)J embryos exhibit head, heart, embryo turning and posterior cranial neural tube and yolk sac vascularization defects and are developmentally delayed.Kctd5em1(IMPC)J/Kctd5em1(IMPC)JC57BL/6NJ-Kctd5em1(IMPC)J/Mmjax
Placental abnormalities in E9.5 Kctd5em1(IMPC)J/Kctd5em1(IMPC)J embryos with diminished spongiotrophoblast layer, abnormal chorioallantoic interface (reduction in allantoic mesoderm), impaired chorioallantoic branching, and multiple labyrinth zone defects.Kctd5em1(IMPC)J/Kctd5em1(IMPC)JC57BL/6NJ-Kctd5em1(IMPC)J/Mmjax
The 3 germ layers have formed appropriately in E8.5 Kctd5em1(IMPC)J/Kctd5em1(IMPC)J embryos.Kctd5em1(IMPC)J/Kctd5em1(IMPC)JC57BL/6NJ-Kctd5em1(IMPC)J/Mmjax
E9.5 Kctd5em1(IMPC)J/Kctd5em1(IMPC)J embryo with an abnormally looped heart, but all 3 germ layers present.Kctd5em1(IMPC)J/Kctd5em1(IMPC)JC57BL/6NJ-Kctd5em1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory