Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Rprd2^em1(IMPC)J
Name:	regulation of nuclear pre-mRNA domain containing 2; endonuclease-mediated mutation 1, Jackson
MGI ID:	MGI:6189568
Synonyms:	Rprd2^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Rprd2^em1(IMPC)J/Rprd2^em1(IMPC)J embryos are developmentally delayed, show impaired embryo turning, abnormal head shape, caudal neural tube kinks and incomplete cranial neural tube closure, abnormal heart morphology and abnormal yolk sacs.	Rprd2^em1(IMPC)J/Rprd2^em1(IMPC)J	C57BL/6NJ-Rprd2^em1(IMPC)J/Mmjax
	Placental abnormalities in Rprd2^em1(IMPC)J/Rprd2^em1(IMPC)J (-/-) embryos include diminished spongiotrophoblast layer, abnormal chorioallantoic interface, impaired chorioallantoic branching, and multiple labyrinth zone defects.	Rprd2^em1(IMPC)J/Rprd2^em1(IMPC)J	C57BL/6NJ-Rprd2^em1(IMPC)J/Mmjax
	E8.5 Rprd2^em1(IMPC)J/Rprd2^em1(IMPC)J embryos are slightly delayed but display typical germ layer patterning.	Rprd2^em1(IMPC)J/Rprd2^em1(IMPC)J	C57BL/6NJ-Rprd2^em1(IMPC)J/Mmjax
	E9.5 Rprd2^em1(IMPC)J/Rprd2^em1(IMPC)J embryos are delayed yet they maintain appropriate expression of key markers in all 3 germ lineages.	Rprd2^em1(IMPC)J/Rprd2^em1(IMPC)J	C57BL/6NJ-Rprd2^em1(IMPC)J/Mmjax

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