Phenotype Images associated with this Allele - MGI

About Help FAQ

Phenotype Images associated with this Allele

Nomenclature

Symbol:	Ireb2^tm1.1Eal
Name:	iron responsive element binding protein 2; targeted mutation 1.1, Elizabeth A Leibold
MGI ID:	MGI:5702744
Synonyms:	Irp2^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Iron accumulates in specific brain regions of Ireb2^tm1.1Eal/Ireb2^tm1.1Eal mice	Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal
	Iron accumulates in axons and oliogodendrocyte cell bodies of Ireb2^tm1.1Eal/Ireb2^tm1.1Eal mice	Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal
	Iron is reduced in Purkinje neurons and in CA1 pyramidal neurons of Ireb2^tm1.1Eal/Ireb2^tm1.1Eal mice	Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal
	Ferritin expression is increased in Ireb2^tm1.1Eal/Ireb2^tm1.1Eal neurons	Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal
	Presence of Protoporphyrin IX-containing granules in the common bile duct of Ireb2^tm1.1Eal/Ireb2^tm1.1Eal mice	Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal
	Iron accumulation in hippocampus and cerebellum of aged Ireb2^tm1.1Eal/Ireb2^tm1.1Eal mice	Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23