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Phenotype Images associated with this Allele
Nomenclature
Symbol: Polgtm1Jiha
Name: polymerase (DNA directed), gamma; targeted mutation 1, Jun-Ichi Hayashi
MGI ID: MGI:5502688
Synonyms: m mutator, mtDNA mutator
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mitochondrial respiration defects in Polgtm1Jiha/Polg+, Polgtm1Jiha/Polgtm1Jiha, and Del(MTmt-Tk-mt-Nd5)1Jiha micePolgtm1Jiha/Polgtm1Jihainvolves: C57BL/6JJcl
Polgtm1Jiha/Polg+involves: C57BL/6JJcl
Del(MTmt-Tk-mt-Nd5)1Jihainvolves: C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj
Kyphosis in Polgtm1Jiha/Polgtm1Jiha and Del(MTmt-Tk-mt-Nd5)1Jiha micePolgtm1Jiha/Polgtm1Jihainvolves: C57BL/6JJcl
Del(MTmt-Tk-mt-Nd5)1Jihainvolves: C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj
Macroscopic tumor-like abnormalities in spleen, liver and/or lymph nodes of Polgtm1Jiha/Polg+ micePolgtm1Jiha/Polg+involves: C57BL/6JJcl
B-cell lymphoma development in Polgtm1Jiha/Polg+ micePolgtm1Jiha/Polg+involves: C57BL/6JJcl

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory