Phenotype Image Detail

Image

Caption

(B) Comparison of the phenotypes observed in Polg^tm1Jiha/Polg^tm1Jiha (m/m mouse), Del(MTmt-Tk-mt-Nd5)1Jiha (Mito-miceDelta), and wild-type (WT) mice at 9 months of age. Kyphosis was observed in homozygous (m/m) mutator mice and mito-miceDelta, while hair graying and hair loss (alopecia) were not observed.

Copyright

This image is from Mito T, PLoS One 2013;8(2):e55789, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199416

Associated Alleles

Symbol	Name
Del(MTmt-Tk-mt-Nd5)1Jiha	deletion, MT, Jun-Ichi Hayashi 1
Polg^tm1Jiha	polymerase (DNA directed), gamma; targeted mutation 1, Jun-Ichi Hayashi

Associated Genotypes

Allelic Composition	Genetic Background
Polg^tm1Jiha/Polg^tm1Jiha	involves: C57BL/6JJcl
Del(MTmt-Tk-mt-Nd5)1Jiha	involves: C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj