About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Mirc21tm1.1Kry
Name: microRNA cluster 21, including Mir34c through Mir34b; targeted mutation 1.1, Gerard Karsentry
MGI ID: MGI:5427919
Synonyms: miR-34bcfl
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Increased bone mass in Mir34atm1.1Kry/Mir34atm1.1Kry Mirc21tm1.1Kry/Mirc21tm1.1Kry Tg(Col1a1-cre)1Kry/0 miceMir34atm1.1Kry/Mir34atm1.1Kry
Mirc21tm1.1Kry/Mirc21tm1.1Kry
Tg(Col1a1-cre)1Kry/0		involves: 129S4/SvJaeSor * 129S6/SvEvTac * FVB/N
Increased bone mass in Mirc21tm1.1Kry/Mirc21tm1.1Kry Tg(Col1a1-cre)1Kry/0 miceMirc21tm1.1Kry/Mirc21tm1.1Kry
Tg(Col1a1-cre)1Kry/0		involves: 129S4/SvJaeSor * 129S6/SvEvTac * FVB/N
Increased osteoblast proliferation in Mirc21tm1.1Kry/Mirc21tm1.1Kry Tg(Col1a1-cre)1Kry/0 mice and decreased proliferation in Tg(Col1a1-Mir34c)#Kry/0 miceTg(Col1a1-Mir34c)#Kry/0B6.Cg-Tg(Col1a1-Mir34c)#Kry
Mirc21tm1.1Kry/Mirc21tm1.1Kry
Tg(Col1a1-cre)1Kry/0		involves: 129S4/SvJaeSor * 129S6/SvEvTac * FVB/N
Increased osteoblast differentiation in Mirc21tm1.1Kry/Mirc21tm1.1Kry Tg(Col1a1-cre)1Kry/0 miceMirc21tm1.1Kry/Mirc21tm1.1Kry
Tg(Col1a1-cre)1Kry/0		involves: 129S4/SvJaeSor * 129S6/SvEvTac * FVB/N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory