Phenotype Images associated with this Allele - MGI

About Help FAQ

Phenotype Images associated with this Allele

Nomenclature

Symbol:	Cryba1^{tm1a(EUCOMM)Hmgu}
Name:	crystallin, beta A1; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
MGI ID:	MGI:4951042
Synonyms:	beta3-, betaA3 KO

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Nuclear cataracts in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} mice	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Nuclear degradation process is impaired in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} mice	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Autophagic markers accumulate in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} mice	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Mitochondria accumulate in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} mice	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Fusion of autophagosomes with lysosomes in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} mouse lenses	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Calcium level is altered in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} lens epithelial cells	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Integrity of cytoskeletal network is affected in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} lenses	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N
	Calpain-3 is activated in Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu} lenses	Cryba1^{tm1a(EUCOMM)Hmgu}/Cryba1^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6J * C57BL/6N

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23