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Phenotype Images associated with this Allele
Nomenclature
Symbol: Cx3cr1tm1Litt
Name: chemokine (C-X3-C motif) receptor 1; targeted mutation 1, Dan R Littman
MGI ID: MGI:2670351
Synonyms: CX3CR1-, CX3CR1EGFP, CX3CR1-EGFP, Cx3cr1gfp, CX3CR1GFP, CX3CR1-GFP, CX3CR-GFP
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Retinal lesion in Ccl2tm1Rol/Ccl2tm1Rol Cx3cr1tm1Litt/Cx3cr1tm1Litt miceCcl2tm1Rol/Ccl2tm1Rol
Cx3cr1tm1Litt/Cx3cr1tm1Litt
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J
Retinal pigment epithelium damage, photoreceptor degeneration and amacrine cell alteration in Ccl2tm1Rol/Ccl2tm1Rol Cx3cr1tm1Litt/Cx3cr1tm1Litt miceCcl2tm1Rol/Ccl2tm1Rol
Cx3cr1tm1Litt/Cx3cr1tm1Litt
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J
Increased Bruch membrane thickness, vacuolated changes in retinal pigment epithelium, photoreceptor inner segment damage and outer segment disorientation in Ccl2tm1Rol/Ccl2tm1Rol Cx3cr1tm1Litt/Cx3cr1tm1Litt eyesCcl2tm1Rol/Ccl2tm1Rol
Cx3cr1tm1Litt/Cx3cr1tm1Litt
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J
Retinal microglial activation in different ages of Ccl2tm1Rol/Ccl2tm1Rol Cx3cr1tm1Litt/Cx3cr1tm1Litt miceCcl2tm1Rol/Ccl2tm1Rol
Cx3cr1tm1Litt/Cx3cr1tm1Litt
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/17/2023
MGI 6.22
The Jackson Laboratory