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Phenotype Images associated with this Allele
Nomenclature
Symbol: Crxtm1Clc
Name: cone-rod homeobox; targeted mutation 1, Constance L Cepko
MGI ID: MGI:2181191
Synonyms: Crx-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Crxtm1.1Smgc/Crxtm1.1Smgc, Crxtm2.1Smgc/Crxtm2.1Smgc, and Crxtm1Clc/Crxtm1Clc mice develop Leber Congenital Amaurosis-like retinopathyCrxtm1Clc/Crxtm1Clcinvolves: 129S6/SvEvTac
Crxtm1.1Smgc/Crxtm1.1SmgcB6.129X1(CBA)-Crxtm1.1Smgc
Crxtm2.1Smgc/Crxtm2.1SmgcB6.129X1(CBA)-Crxtm2.1Smgc
Photoreceptor abnormalities in CrxRip/Crx+, CrxRip/CrxRip, and Crxtm1Clc/Crxtm1Clc retinasCrxRip/Crx+C57BL/6J-CrxRip
CrxRip/CrxRipC57BL/6J-CrxRip
Crxtm1Clc/Crxtm1Clcinvolves: 129S6/SvEvTac * C57BL/6J
Abnormal photoreceptor segments in CrxRip/Crx+, CrxRip/CrxRip, and Crxtm1Clc/Crxtm1Clc miceCrxRip/Crx+C57BL/6J-CrxRip
CrxRip/CrxRipC57BL/6J-CrxRip
Crxtm1Clc/Crxtm1Clcinvolves: 129S6/SvEvTac * C57BL/6J
Outer retina microscopy of Crxtm1Clc/Crxtm1Clc miceCrxtm1Clc/Crxtm1Clcinvolves: 129S6/SvEvTac
Outer segment micrograph of Crxtm1Clc/Crxtm1Clc retinaCrxtm1Clc/Crxtm1Clcinvolves: 129S6/SvEvTac
Crxtm1Clc/Crxtm1Clc retina and outer segment layer micrographs at P21 and P10Crxtm1Clc/Crxtm1Clcinvolves: 129S6/SvEvTac
Outer segment morphogenesis in Crxtm1Clc/Crxtm1Clc photoreceptorsCrxtm1Clc/Crxtm1Clcinvolves: 129S6/SvEvTac
Photoreceptor layer micrographs of Crxtm1Clc/Crxtm1Clc retinaCrxtm1Clc/Crxtm1Clcinvolves: 129S6/SvEvTac
Outer plexiform layer micrographs of Crxtm1Clc/Crxtm1Clc mouse retinaCrxtm1Clc/Crxtm1Clcinvolves: 129S6/SvEvTac
Transmission electron micrographs of the outer plexiform layer in Crxtm1Clc/Crxtm1Clc retinas at P21Crxtm1Clc/Crxtm1Clcinvolves: 129S6/SvEvTac
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory