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Phenotype Images associated with this Allele
Nomenclature
Symbol: Leprdb
Name: leptin receptor; diabetes
MGI ID: MGI:1856009
Synonyms: db, db/db, Lepdb, Lepr-, leprdb, Leprdb-1J
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Increased beta cell mass in Leprdb/Leprdb mice and Leprdb/Leprdb Cebpbtm1.1Maka/Cebpbtm1.1Maka Tg(Ins2-cre)23Herr/0 miceLeprdb/LeprdbBKS.Cg-Dock7m +/+ Leprdb/Jcl
Cebpbtm1.1Maka/Cebpbtm1.1Maka
Leprdb/Leprdb
Tg(Ins2-cre)23Herr/0
involves: 129P2/OlaHsd * C57BL/6J * C57BLKS/J * CBA/J
Neural-specific STAT3 deletion results in severe obesity in Stat3tm1Flv/Stat3tm1Flv Tg(Nes-cre)1Kln/0 mice similar to that seen in Leprdb/Leprdb miceLeprdb/Leprdbinvolves: C57BLKS/J
Stat3tm1Flv/Stat3tm1Flv
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * SJL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/17/2023
MGI 6.22
The Jackson Laboratory