Phenotype Image Detail

Image

Caption

C, X-ray analysis of femur bones harvested from Ghr^tm1.1Masp/Ghr^tm1.1Masp Speer6-ps1^{Tg(Alb-cre)21Mgn}/0 (GHRLD) mice and control littermates, showing that the mutant mice have less bone density. D, examples of micro-CT images of femurs from mutant mice and controls. E, quantification of bone volume of GHRLD femurs based on micro-CT image analysis. ***, p<0.002. Error bars indicate mean +/- S.E.

This image is from Fan Y, J Biol Chem 2009 Jul 24;284(30):19937-44 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:152627

Associated
Alleles

Symbol	Name
Ghr^tm1.1Masp	growth hormone receptor; targeted mutation 1.1, Mark A Sperling
Speer6-ps1^{Tg(Alb-cre)21Mgn}	spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson

Associated
Genotypes

Allelic Composition	Genetic Background
Ghr^tm1.1Masp/Ghr^tm1.1Masp Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺	involves: 129S4/SvJaeSor * C57BL/6 * DBA

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