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| Caption | Hematoxylin and eosin stained sections of the intestines of P14 control (WT) and Itgb1tm1Efu/Itgb1tm1Efu Tg(Vil1-cre)997Gum/0 mice (KO) littermates. Duodenal (A and B) and ileal (C and D) sections show markedly enlarged crypts (arrowheads) and villi (arrows) in the mutant mice (B and D) compared with those of the control littermate (A and C). m, muscularis layers. Normal crypts in the control mice are shown in the insets (A,C and E). Dysplastic crypts in the mutant mice are outlined by dashed lines (B,D and F). Sections through the cecum (large intestine) from a mutant mouse shows marked crypt hyperplasia (arrowheads in F) and dysplasia (dashed line) compared with a control littermate (E). Bars, 0.1 mm. | ||||||
| Copyright | This image is from Jones RG, J Cell Biol 2006 Nov 6;175(3):505-14, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:119155 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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