Gene Expression Image Detail

Reference

Figure

ID

J:80765 Romand R, et al., Mech Dev. 2002 Dec;119(2):213-23

1

MGI:5460864

Image

Caption

RNA in situ hybridization at E10.5 on sagittal sections (A-C) and frontal sections at E12.5 (D-F), E14.5 (G-H) and E18.5 (I-M). Expression domains were visualized as computer superimpositions of brightfield views showing histology (toluidine blue staining) and darkfield views revealing the signal grains in false red-brown color. (I) Arrows indicate the organ of Corti; arrowhead indicates the spiral limbus. Double asterisks indicate the basal turn and a single asterisk indicates the upper turn of the cochlea. (J,M) Arrows indicate the basilar membranes. (K) Arrows indicate the stria vascularis; arrowheads indicate the epithelium lining the middle ear cavity; large arrows indicate the otic capsule (large arrows). Abbreviations: An, Auditory nerve; Cc, cochlear canal; Ed, endolymphatic duct; Hb, hindbrain; Ko, Kolliker's organ; Mo, modiolus; Oc, otic capsule; Or, organ of Corti; Ot, otocyst; Rs, Reissner membrane; Sg, spiral ganglion; Sli, inner spiral limbus; Vc, vestibular canal. Scale bars: 200 um (A-K) and 50 um (L,M).

Copyright

Reprinted with permission from Elsevier from 10.1016/S0925-4773(02)00385-4 Mech Dev 119: 213-23, Romand R; Hashino E; Dolle P; Vonesch JL; Chambon P; Ghyselinck NB, The retinoic acid receptors RARalpha and RARgamma are required for inner ear development. Copyright 2002

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A	MGI:5460878 (Rara)
B	MGI:5460882 (Rarb)
C	MGI:5460884 (Rarg)
D	MGI:5460878 (Rara)
E	MGI:5460882 (Rarb)
F	MGI:5460884 (Rarg)
G	MGI:5460882 (Rarb)
H	MGI:5460884 (Rarg)
I	MGI:5460878 (Rara)
J	MGI:5460882 (Rarb)
K	MGI:5460884 (Rarg)
L	MGI:5460878 (Rara)
M	MGI:5460882 (Rarb)