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Gene Expression Data
Assay Details
Assay
Reference: J:80765 Romand R, et al., The retinoic acid receptors RARalpha and RARgamma are required for inner ear development. Mech Dev. 2002 Dec;119(2):213-23
Assay type: RNA in situ
MGI Accession ID: MGI:5460878
Gene symbol: Rara
Gene name: retinoic acid receptor, alpha
Probe: mRAR-alpha
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst Absent 1A
TS17: hindbrain Present Regionally restricted 1A Expression was detected in the dorsal portion.

Specimen 1D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: inner ear epithelium Present Regionally restricted 1D Expression was detected along both sides of the otocyst epithelium.
TS20: inner ear mesenchyme Present Non-Uniform 1D Expression was detected in the mesenchyme surrounding the otocyst. Some regions had lower expression levels.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlea Present Expression was less abundant than at E12.5.
TS22: inner ear vestibular component Present Expression was less abundant than at E12.5.

Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cochlea Present Expression was less abundant than at E12.5.
TS24: inner ear vestibular component Present Expression was less abundant than at E12.5.

Specimen 1I: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cochlear ganglion Present 1I
TS26: organ of Corti Present 1I
TS26: cochlear duct Present Regionally restricted 1I Expression was detected in the inner spiral limbus.
TS26: cochlea Present Non-Uniform 1I Expression was lower in the basal turn than in the upper turn of the cochlea.

Specimen 1L: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: organ of Corti Present 1L

Specimen 2A: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cochlear ganglion Present 2A
TS28: organ of Corti Present 2A
TS28: vestibulocochlear nerve cochlear component Present 2A
TS28: stria vascularis Weak 2A

Specimen 2C: postnatal month 3 (more )
Structure Level Pattern Image Note
TS28: spiral ligament Strong 2C
TS28: stria vascularis Strong 2C
TS28: vestibulocochlear nerve cochlear component Strong 2C
TS28: cochlear ganglion Weak 2C
TS28: organ of Corti Weak 2C
TS28: otic capsule Weak 2C
TS28: spiral limbus Weak 2C


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory