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Gene Expression Data
Assay Details
Assay
Reference: J:80765 Romand R, et al., The retinoic acid receptors RARalpha and RARgamma are required for inner ear development. Mech Dev. 2002 Dec;119(2):213-23
Assay type: RNA in situ
MGI Accession ID: MGI:5460884
Gene symbol: Rarg
Gene name: retinoic acid receptor, gamma
Probe: mRAR-gamma
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: endolymphatic appendage mesenchyme Present Regionally restricted 1C Expression was detected in the mesenchyme around the presumptive endolymphatic duct.
TS17: branchial arch Present 1C
TS17: hindbrain Absent 1C
TS17: otocyst epithelium Absent 1C

Specimen 1F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: inner ear mesenchyme Present Regionally restricted 1F Expression was confined to the mesenchyme surrounding the otocyst epithelium, with higher expression along the lateral side of the otocyst.
TS20: otic capsule Present Regionally restricted 1F Expression was detected over large areas in the mesenchyme of the presumptive otic capsule.

Specimen 1H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: otic capsule Strong Graded 1H Expression was strong in the otic capsule with a base to apex gradient; labeling was much weaker at the base of the capsule.
TS22: cochlear duct epithelium Absent 1H No expression was detected in sensory epithelium of the cochlear canal.

Specimen 1K: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cochlear duct Present Regionally restricted 1K Expression was detected in the inner spiral limbus and the stria vascularis.
TS26: cochlea Present Regionally restricted 1K Expression was detected in the modiolus.
TS26: pharyngo-tympanic tube epithelium Present Regionally restricted 1K Expression was detected in the epithelium lining the middle ear cavity.
TS26: otic capsule Present Regionally restricted 1K Expression was detected along the external and internal borders of the otic capsule.
TS26: cochlear ganglion Absent 1K
TS26: vestibulocochlear nerve cochlear component Absent 1K

Specimen 2D: postnatal month 3 (more )
Structure Level Pattern Image Note
TS28: cochlear ganglion Present 2D
TS28: spiral ligament Present 2D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory