Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TGFBR2	HGNC:11773 (HGNC) 7048 (Entrez Gene) 190182 (OMIM) TGFBR2 (Alliance of Genome Resources)	Chr3 p24.1	Chr3:30606356-30694142 (+) GRCh38	colon cancer esophageal cancer hereditary nonpolyposis colorectal cancer type 6 Loeys-Dietz syndrome 2 Lynch syndrome Marfan syndrome mismatch repair cancer syndrome pancreatic cancer	P37173 (UniProt | EBI) NM_001407130 (RefSeq)
mouse	Tgfbr2	MGI:98729 (MGI) 21813 (Entrez Gene) Gene Tree Tgfbr2 (Alliance of Genome Resources)	Chr9 68.39 cM	Chr9:115916763-116004431 (-) GRCm39	cleft soft palate DiGeorge syndrome Loeys-Dietz syndrome prostate cancer	21813 (NCBI Gene Model) Q62312 (UniProt | EBI) NM_009371 (RefSeq)
rat	Tgfbr2	RGD:69651 (Rat Genome Database) 81810 (Entrez Gene) Tgfbr2 (Alliance of Genome Resources)	Chr8 q32			P38438 (UniProt | EBI) NM_031132 (RefSeq)
zebrafish	tgfbr2b	ZDB-GENE-980526-375 (Zebrafish Model Organism Database) 30739 (Entrez Gene) tgfbr2b (Alliance of Genome Resources)	Chr16			NP_878275 (RefSeq) NM_182855 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.