Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TRPM4	HGNC:17993 (HGNC) 54795 (Entrez Gene) 606936 (OMIM) TRPM4 (Alliance of Genome Resources)	Chr19 q13.33	Chr19:49157741-49211836 (+) GRCh38	erythrokeratodermia variabilis et progressiva 6 progressive familial heart block type IB	Q8TD43 (UniProt | EBI) NM_001321282 (RefSeq)
mouse	Trpm4	MGI:1915917 (MGI) 68667 (Entrez Gene) Gene Tree Trpm4 (Alliance of Genome Resources)	Chr7 29.24 cM	Chr7:44952579-44983495 (-) GRCm39		68667 (NCBI Gene Model) Q7TN37 (UniProt | EBI) NM_175130 (RefSeq)
rat	Trpm4	RGD:620244 (Rat Genome Database) 171143 (Entrez Gene) Trpm4 (Alliance of Genome Resources)	Chr1 q22			Q9ESQ5 (UniProt | EBI) NM_133607 (RefSeq)
zebrafish	trpm4a	ZDB-GENE-090302-3 (Zebrafish Model Organism Database) 100004946 (Entrez Gene) trpm4a (Alliance of Genome Resources)	Chr3			NP_001275744 (RefSeq) NM_001288815 (RefSeq)
	trpm4b.1	ZDB-GENE-061214-3 (Zebrafish Model Organism Database) 102659287 (Entrez Gene) trpm4b.1 (Alliance of Genome Resources)	Chr12			XP_021335886 (RefSeq)
	trpm4b.2	ZDB-GENE-061214-2 (Zebrafish Model Organism Database) 799647 (Entrez Gene) trpm4b.2 (Alliance of Genome Resources)	Chr12			NP_001269082 (RefSeq) NM_001282153 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.