Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HCCS	HGNC:4837 (HGNC) 3052 (Entrez Gene) 300056 (OMIM) HCCS (Alliance of Genome Resources)	ChrX p22.2	ChrX:11111301-11123086 (+) GRCh38	linear skin defects with multiple congenital anomalies 1 microphthalmia	P53701 (UniProt | EBI) NM_001122608 (RefSeq)
mouse	Hccs	MGI:106911 (MGI) 15159 (Entrez Gene) Gene Tree Hccs (Alliance of Genome Resources)	ChrX 78.98 cM	ChrX:168094526-168103361 (-) GRCm39	microphthalmia	15159 (NCBI Gene Model) P53702 (UniProt | EBI) NM_001410431 (RefSeq)
rat	Hccs	RGD:1563855 (Rat Genome Database) 317444 (Entrez Gene) Hccs (Alliance of Genome Resources)	ChrX q13			NP_001178661 (RefSeq) NM_001191732 (RefSeq)
zebrafish	hccsa.1	ZDB-GENE-040718-202 (Zebrafish Model Organism Database) 436771 (Entrez Gene) hccsa.1 (Alliance of Genome Resources)	Chr2			NP_001002498 (RefSeq) NM_001002498 (RefSeq)
	hccsa.2	ZDB-GENE-090501-4 (Zebrafish Model Organism Database) 101882578 (Entrez Gene) hccsa.2 (Alliance of Genome Resources)	Chr2			XP_017208122 (RefSeq)
	hccsb	ZDB-GENE-000607-78 (Zebrafish Model Organism Database) 58016 (Entrez Gene) hccsb (Alliance of Genome Resources)	Chr24			NP_958859 (RefSeq) NM_201451 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.