Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HCCS
  • Mouse genes Hccs
  • Rat genes Hccs
  • Zfish genes hccsa.1,hccsa.2,hccsb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hccs

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0020037	heme binding	HCCS	IDA		Human	PMID:23150584
Molecular Function	GO:0004408	holocytochrome-c synthase activity	HCCS	IDA		Human	PMID:23150584
Molecular Function	GO:0005515	protein binding	HCCS	IPI	UniProtKB:Q13596	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HCCS	IPI	UniProtKB:Q9HC62	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HCCS	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HCCS	IPI	UniProtKB:P06307	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HCCS	IPI	UniProtKB:Q9Y371	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Hccs	IPI	UniProtKB:P51906	Mouse	PMID:16858406
Molecular Function	GO:0005515	protein binding	Hccs	IPI	UniProtKB:Q60989	Mouse	PMID:16858406
Cellular Component	GO:0005829	cytosol	Hccs	IDA		Mouse	PMID:16858406
Cellular Component	GO:0016020	membrane	HCCS	IDA		Human	PMID:23150584
Cellular Component	GO:0005739	mitochondrion	HCCS	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	HCCS	IDA		Human	PMID:11827457
Cellular Component	GO:0005739	mitochondrion	Hccs	IDA		Mouse	PMID:16858406
Cellular Component	GO:0005739	mitochondrion	Hccs	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Hccs	HDA		Mouse	PMID:18614015
Biological Process	GO:0018063	cytochrome c-heme linkage	HCCS	IDA		Human	PMID:23150584

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern