Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	BDNF	HGNC:1033 (HGNC) 627 (Entrez Gene) 113505 (OMIM) BDNF (Alliance of Genome Resources)	Chr11 p14.1	Chr11:27654893-27722058 (-) GRCh38	Alzheimer's disease asthma atopic dermatitis cognitive disorder color blindness congenital central hypoventilation syndrome glaucoma Huntington's disease obsessive-compulsive disorder obstructive sleep apnea Parkinsonism post-traumatic stress disorder rhinitis status epilepticus	P23560 (UniProt | EBI) NM_001143810 (RefSeq)
mouse	Bdnf	MGI:88145 (MGI) 12064 (Entrez Gene) Gene Tree Bdnf (Alliance of Genome Resources)	Chr2 56.63 cM	Chr2:109505045-109557352 (+) GRCm39		ENSMUSG00000048482 (Ensembl Gene Model) ENSMUSP00000106671 (Ensembl) ENSMUST00000111042 (Ensembl)
rat	Bdnf	RGD:2202 (Rat Genome Database) 24225 (Entrez Gene) Bdnf (Alliance of Genome Resources)	Chr3 q34			P23363 (UniProt | EBI) NM_001270637 (RefSeq)
zebrafish	bdnf	ZDB-GENE-000412-1 (Zebrafish Model Organism Database) 58118 (Entrez Gene) bdnf (Alliance of Genome Resources)	Chr7			NP_001295578 (RefSeq) NM_131595 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.