Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MT-CO1
  • Mouse genes mt-Co1
  • Rat genes Mt-co1
  • Zfish genes mt-co1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set mt-Co1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004129	cytochrome-c oxidase activity	MT-CO1	IMP		Human	PMID:12140182
Molecular Function	GO:0004129	cytochrome-c oxidase activity	mt-Co1	IDA		Mouse	PMID:18729827
Molecular Function	GO:0005515	protein binding	MT-CO1	IPI	UniProtKB:Q66K74	Human	PMID:12762840
Molecular Function	GO:0005515	protein binding	MT-CO1	IPI	UniProtKB:P13073	Human	PMID:23260140
Molecular Function	GO:0005515	protein binding	MT-CO1	IPI	UniProtKB:Q9BVV7	Human	PMID:23260140
Molecular Function	GO:0005515	protein binding	MT-CO1	IPI	UniProtKB:Q9Y2R0	Human	PMID:23260140
Molecular Function	GO:0005515	protein binding	MT-CO1	IPI	UniProtKB:P13073,UniProtKB:Q15526,UniProtKB:Q8N5G0,UniProtKB:Q9Y2R0	Human	PMID:26321642
Molecular Function	GO:0005515	protein binding	MT-CO1	IPI	UniProtKB:Q53S58	Human	PMID:29154948
Cellular Component	GO:0005743	mitochondrial inner membrane	mt-Co1	IDA		Mouse	PMID:16815968
Cellular Component	GO:0005750	mitochondrial respiratory chain complex III	MT-CO1	IDA		Human	PMID:23168492
Cellular Component	GO:0005751	mitochondrial respiratory chain complex IV	MT-CO1	IPI		Human	PMID:30030519
Cellular Component	GO:0005751	mitochondrial respiratory chain complex IV	MT-CO1	IMP		Human	PMID:19393246
Cellular Component	GO:0005751	mitochondrial respiratory chain complex IV	MT-CO1	IDA		Human	PMID:23168492
Cellular Component	GO:0005751	mitochondrial respiratory chain complex IV	mt-Co1	IDA		Mouse	PMID:24154540
Cellular Component	GO:0005739	mitochondrion	mt-Co1	IDA		Mouse	PMID:26644517
Cellular Component	GO:0005739	mitochondrion	mt-Co1	IDA		Mouse	PMID:15582606
Cellular Component	GO:0005739	mitochondrion	mt-Co1	IDA		Mouse	PMID:12943672
Cellular Component	GO:0005739	mitochondrion	mt-Co1	IDA		Mouse	PMID:16336229
Cellular Component	GO:0005739	mitochondrion	mt-Co1	IDA		Mouse	PMID:19837698
Cellular Component	GO:0005739	mitochondrion	mt-Co1	IDA		Mouse	PMID:11940593
Cellular Component	GO:0005739	mitochondrion	mt-Co1	IDA		Mouse	PMID:16103131
Cellular Component	GO:0005739	mitochondrion	mt-Co1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Mt-co1	IDA		Rat	PMID:18567746|RGD:2302302
Cellular Component	GO:0045277	respiratory chain complex IV	MT-CO1	IDA		Human	PMID:1651240
Biological Process	GO:0007568	aging	Mt-co1	IEP		Rat	PMID:9701770|RGD:2302303
Biological Process	GO:0021549	cerebellum development	Mt-co1	IEP		Rat	PMID:2465379|RGD:2302317
Biological Process	GO:0046686	response to cadmium ion	mt-co1	IEP		Zfish	PMID:16799861
Biological Process	GO:0046688	response to copper ion	Mt-co1	IEP		Rat	PMID:18567746|RGD:2302302
Biological Process	GO:0051602	response to electrical stimulus	Mt-co1	IEP		Rat	PMID:14519661|RGD:2302297
Biological Process	GO:0051597	response to methylmercury	mt-co1	IDA		Zfish	PMID:15984772
Biological Process	GO:0006979	response to oxidative stress	Mt-co1	IDA		Rat	PMID:17870132|RGD:2302295

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern