Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZNRF1
  • Mouse genes Znrf1
  • Rat genes Znrf1
  • Zfish genes znrf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Znrf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P51668	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P51965	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P61077	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P61088	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P62837	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:Q13404	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:Q9Y2X8	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P51668	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P51965	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P61077	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P61088	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P62837	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:Q9Y2X8	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P61088	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:O94888	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P51668	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:P62837	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZNRF1	IPI	UniProtKB:Q9Y2X8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Znrf1	IPI	UniProtKB:P31750	Mouse	MGI:MGI:5306704|PMID:22057101
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ZNRF1	IDA		Human	PMID:22797923
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Znrf1	IDA		Mouse	PMID:22057101
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Znrf1	IDA		Mouse	MGI:MGI:5306704|PMID:22057101
Cellular Component	GO:0005829	cytosol	ZNRF1	IDA		Human	PMID:22797923
Cellular Component	GO:0005768	endosome	ZNRF1	IDA		Human	GO_REF:0000054
Cellular Component	GO:0016020	membrane	ZNRF1	IDA		Human	PMID:22797923
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Znrf1	IDA		Mouse	MGI:MGI:5306704|PMID:22057101
Biological Process	GO:0070936	protein K48-linked ubiquitination	Znrf1	IDA		Mouse	MGI:MGI:5306704|PMID:22057101

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern