Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZMYND8
  • Mouse genes Zmynd8
  • Rat genes Zmynd8
  • Zfish genes prkcbp1l,zmynd8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zmynd8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070577	lysine-acetylated histone binding	ZMYND8	IDA		Human	PMID:27477906
Molecular Function	GO:0035064	methylated histone binding	ZMYND8	IDA		Human	PMID:27477906
Molecular Function	GO:0005515	protein binding	ZMYND8	IPI	UniProtKB:Q9Y613	Human	PMID:15095401
Molecular Function	GO:0005515	protein binding	ZMYND8	IPI	UniProtKB:P41182	Human	PMID:16147992
Molecular Function	GO:0005515	protein binding	ZMYND8	IPI	UniProtKB:Q93009	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	ZMYND8	IPI	UniProtKB:Q86YP4	Human	PMID:27732854
Molecular Function	GO:0005515	protein binding	ZMYND8	IPI	UniProtKB:Q16643	Human	PMID:28966017
Molecular Function	GO:0005515	protein binding	ZMYND8	IPI	UniProtKB:O60563	Human	PMID:30134174
Molecular Function	GO:0005515	protein binding	ZMYND8	IPI	UniProtKB:Q14839	Human	PMID:30134174
Molecular Function	GO:0005515	protein binding	ZMYND8	IPI	UniProtKB:Q93009	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	ZMYND8	IPI	UniProtKB:Q16643	Human	PMID:35916866
Molecular Function	GO:0005515	protein binding	ZMYND8	IPI	UniProtKB:Q86YP4	Human	PMID:35916866
Molecular Function	GO:0005515	protein binding	Zmynd8	IPI	RGD:70885	Rat	PMID:24117785|RGD:8554267
Molecular Function	GO:0005515	protein binding	Zmynd8	IPI	UniProtKB:Q07266	Rat	PMID:24117785|RGD:8554267
Molecular Function	GO:0019904	protein domain specific binding	ZMYND8	IDA		Human	PMID:28966017
Molecular Function	GO:0003714	transcription corepressor activity	ZMYND8	IMP		Human	PMID:27477906
Molecular Function	GO:0003714	transcription corepressor activity	ZMYND8	IMP		Human	PMID:33323928
Molecular Function	GO:0008270	zinc ion binding	ZMYND8	IDA		Human	PMID:28966017
Cellular Component	GO:0000785	chromatin	ZMYND8	IDA		Human	PMID:25593309
Cellular Component	GO:0000785	chromatin	ZMYND8	IDA		Human	PMID:26655721
Cellular Component	GO:0000785	chromatin	ZMYND8	IDA		Human	PMID:27732854
Cellular Component	GO:0000785	chromatin	ZMYND8	IDA		Human	PMID:30134174
Cellular Component	GO:0000785	chromatin	ZMYND8	IDA		Human	PMID:36064715
Cellular Component	GO:0005737	cytoplasm	ZMYND8	IMP		Human	PMID:28966017
Cellular Component	GO:0005737	cytoplasm	Zmynd8	IDA		Rat	PMID:24117785|RGD:8554267
Cellular Component	GO:0043198	dendritic shaft	Zmynd8	IDA		Rat	PMID:24117785|RGD:8554267
Cellular Component	GO:0043197	dendritic spine	Zmynd8	IDA		Rat	PMID:24117785|RGD:8554267
Cellular Component	GO:0005730	nucleolus	ZMYND8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ZMYND8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ZMYND8	IDA		Human	PMID:27477906
Cellular Component	GO:0005634	nucleus	ZMYND8	IDA		Human	PMID:27732854
Cellular Component	GO:0005634	nucleus	ZMYND8	IDA		Human	PMID:28966017
Cellular Component	GO:0005634	nucleus	Zmynd8	IDA		Rat	PMID:24117785|RGD:8554267
Cellular Component	GO:0090734	site of DNA damage	ZMYND8	IDA		Human	PMID:25593309
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ZMYND8	IMP		Human	PMID:25593309
Biological Process	GO:0098815	modulation of excitatory postsynaptic potential	Zmynd8	IMP		Rat	PMID:24117785|RGD:8554267
Biological Process	GO:0030336	negative regulation of cell migration	ZMYND8	IMP		Human	PMID:27477906
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ZMYND8	IMP		Human	PMID:25593309
Biological Process	GO:0007399	nervous system development	ZMYND8	IMP		Human	PMID:35916866
Biological Process	GO:0060999	positive regulation of dendritic spine development	Zmynd8	IMP		Rat	PMID:24117785|RGD:8554267
Biological Process	GO:1902952	positive regulation of dendritic spine maintenance	Zmynd8	IMP		Rat	PMID:24117785|RGD:8554267
Biological Process	GO:0051491	positive regulation of filopodium assembly	Zmynd8	IMP		Rat	PMID:24117785|RGD:8554267
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	ZMYND8	IMP		Human	PMID:26655721
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	ZMYND8	IPI	UniProtKB:P50750	Human	PMID:30134174
Biological Process	GO:0071168	protein localization to chromatin	ZMYND8	IMP		Human	PMID:25593309
Biological Process	GO:1902897	regulation of postsynaptic density protein 95 clustering	Zmynd8	IMP		Rat	PMID:24117785|RGD:8554267

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern