Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZNF746,ZNF767P
  • Mouse genes Zfp746
  • Rat genes Zfp746
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfp746

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ZNF746	IDA		Human	PMID:21376232
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZNF746	IDA		Human	PMID:21376232
Molecular Function	GO:0005515	protein binding	ZNF746	IPI	UniProtKB:O60260	Human	PMID:21376232
Molecular Function	GO:0005515	protein binding	Zfp746	IPI	UniProtKB:Q9WVS6	Mouse	MGI:MGI:4948386|PMID:21376232
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF746	IDA		Human	PMID:21376232
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ZNF746	IDA		Human	PMID:21376232
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ZNF746	IPI	UniProtKB:O60260	Human	PMID:21376232
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Zfp746	IPI	UniProtKB:Q9WVS6	Mouse	MGI:MGI:4948386|PMID:21376232
Cellular Component	GO:0005737	cytoplasm	ZNF746	IDA		Human	PMID:21376232
Cellular Component	GO:0005829	cytosol	ZNF746	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ZNF746	IDA		Human	GO_REF:0000052
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZNF746	IDA		Human	PMID:21376232
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZNF746	IMP		Human	PMID:31856708
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ZNF746	IDA		Human	PMID:21376232
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Zfp746	IDA		Mouse	MGI:MGI:4948386|PMID:21376232
Biological Process	GO:1901216	positive regulation of neuron death	ZNF746	IDA		Human	PMID:21376232
Biological Process	GO:1901216	positive regulation of neuron death	Zfp746	IGI	UniProtKB:Q9WVS6	Mouse	MGI:MGI:4948386|PMID:21376232
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ZNF746	IDA		Human	PMID:21376232
Biological Process	GO:0051291	protein heterooligomerization	ZNF746	IDA		Human	PMID:31856708
Biological Process	GO:0051260	protein homooligomerization	ZNF746	IDA		Human	PMID:31856708

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern