Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZFHX3
  • Mouse genes Zfhx3
  • Rat genes Zfhx3
  • Zfish genes zfhx3a,zfhx3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfhx3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZFHX3	EXP		Human	PMID:11312261
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZFHX3	IDA		Human	PMID:11314020
Molecular Function	GO:0019899	enzyme binding	ZFHX3	IPI	UniProtKB:Q9Y6X2	Human	PMID:14715251
Molecular Function	GO:0005515	protein binding	ZFHX3	IPI	UniProtKB:Q13761	Human	PMID:20599712
Molecular Function	GO:0005515	protein binding	ZFHX3	IPI	UniProtKB:Q14258	Human	PMID:22452784
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZFHX3	IDA		Human	PMID:7507206
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Zfhx3	IDA		Mouse	MGI:MGI:5660827|PMID:26232227
Cellular Component	GO:0005737	cytoplasm	ZFHX3	IDA		Human	PMID:20599712
Cellular Component	GO:0005737	cytoplasm	Zfhx3	IDA		Rat	PMID:16251211|RGD:1625359
Cellular Component	GO:0005739	mitochondrion	Zfhx3	HDA		Mouse	PMID:14651853
Cellular Component	GO:0016604	nuclear body	ZFHX3	IDA		Human	PMID:24651376
Cellular Component	GO:0005654	nucleoplasm	ZFHX3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ZFHX3	IDA		Human	PMID:20599712
Cellular Component	GO:0005634	nucleus	ZFHX3	IDA		Human	PMID:24651376
Cellular Component	GO:0005634	nucleus	Zfhx3	IDA		Rat	PMID:16251211|RGD:1625359
Cellular Component	GO:0005667	transcription regulator complex	ZFHX3	IDA		Human	PMID:10318867
Biological Process	GO:0007420	brain development	Zfhx3	IEP		Rat	PMID:12926016|RGD:2315699
Biological Process	GO:0032922	circadian regulation of gene expression	Zfhx3	IMP		Mouse	MGI:MGI:5660827|PMID:26232227
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ZFHX3	IDA		Human	PMID:11314020
Biological Process	GO:0045785	positive regulation of cell adhesion	Zfhx3	IMP		Mouse	MGI:MGI:4837978|PMID:20876357
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ZFHX3	IDA		Human	PMID:20599712
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Zfhx3	IMP		Mouse	MGI:MGI:5660827|PMID:26232227
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Zfhx3	IMP		Mouse	MGI:MGI:4837978|PMID:20876357
Biological Process	GO:0051726	regulation of cell cycle	Zfhx3	IEP		Rat	PMID:16251211|RGD:1625359
Biological Process	GO:1904059	regulation of locomotor rhythm	Zfhx3	IMP		Mouse	MGI:MGI:5660827|PMID:26232227
Biological Process	GO:0045664	regulation of neuron differentiation	Zfhx3	IEP		Rat	PMID:16251211|RGD:1625359
Biological Process	GO:0071559	response to transforming growth factor beta	ZFHX3	IDA		Human	PMID:20599712

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern