Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZBTB46
  • Mouse genes Zbtb46
  • Rat genes Zbtb46
  • Zfish genes zbtb46
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zbtb46

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Zbtb46	IDA		Mouse	MGI:MGI:5461437|PMID:22851594
Molecular Function	GO:0005515	protein binding	Zbtb46	IPI	UniProtKB:Q9CQT7	Mouse	MGI:MGI:5508711|PMID:22370726
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Zbtb46	IDA		Mouse	MGI:MGI:5461437|PMID:22851594
Cellular Component	GO:0000785	chromatin	Zbtb46	IDA		Mouse	MGI:MGI:5461437|PMID:22851594
Biological Process	GO:0097028	dendritic cell differentiation	Zbtb46	IMP	MGI:MGI:5320483	Mouse	PMID:22615127
Biological Process	GO:0030851	granulocyte differentiation	Zbtb46	IMP	MGI:MGI:5320483	Mouse	PMID:22615127
Biological Process	GO:0030225	macrophage differentiation	Zbtb46	IMP	MGI:MGI:5320483	Mouse	PMID:22615127
Biological Process	GO:2001199	negative regulation of dendritic cell differentiation	Zbtb46	IMP	MGI:MGI:5320483	Mouse	PMID:22615127
Biological Process	GO:0030853	negative regulation of granulocyte differentiation	Zbtb46	IMP	MGI:MGI:5320483	Mouse	PMID:22615127
Biological Process	GO:0002695	negative regulation of leukocyte activation	Zbtb46	IMP	MGI:MGI:5320483	Mouse	PMID:22615127
Biological Process	GO:0045650	negative regulation of macrophage differentiation	Zbtb46	IMP	MGI:MGI:5320483	Mouse	PMID:22615127
Biological Process	GO:0045656	negative regulation of monocyte differentiation	Zbtb46	IMP	MGI:MGI:5320483	Mouse	PMID:22615127
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Zbtb46	IDA		Mouse	MGI:MGI:5461437|PMID:22851594
Biological Process	GO:0002273	plasmacytoid dendritic cell differentiation	Zbtb46	IMP	MGI:MGI:5320483	Mouse	PMID:22615127
Biological Process	GO:2001200	positive regulation of dendritic cell differentiation	Zbtb46	IMP	MGI:MGI:5320483	Mouse	PMID:22615127
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ZBTB46	IDA		Human	PMID:29884909

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern