Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZBTB18
  • Mouse genes Zbtb18
  • Rat genes Zbtb18
  • Zfish genes zbtb18
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zbtb18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZBTB18	IDA		Human	PMID:9756912
Molecular Function	GO:0005515	protein binding	ZBTB18	IPI	UniProtKB:P56545-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ZBTB18	IPI	UniProtKB:P56545-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB18	IPI	UniProtKB:Q8N680	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB18	IPI	UniProtKB:Q8WY64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB18	IPI	UniProtKB:Q92569	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ZBTB18	IPI	UniProtKB:P56545	Human	PMID:35800763
Molecular Function	GO:0043565	sequence-specific DNA binding	ZBTB18	IDA		Human	PMID:9756912
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ZBTB18	IDA		Human	PMID:28473536
Cellular Component	GO:0000792	heterochromatin	ZBTB18	IDA		Human	PMID:9756912
Cellular Component	GO:0016607	nuclear speck	ZBTB18	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ZBTB18	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ZBTB18	IDA		Human	PMID:25796446
Cellular Component	GO:0005634	nucleus	Zbtb18	IDA		Mouse	PMID:18262495
Cellular Component	GO:0005634	nucleus	Zbtb18	IDA		Mouse	PMID:19409883
Biological Process	GO:0021549	cerebellum development	Zbtb18	IMP	MGI:MGI:3851929	Mouse	PMID:19409883
Biological Process	GO:0021987	cerebral cortex development	Zbtb18	IMP	MGI:MGI:3851929	Mouse	PMID:19409883
Biological Process	GO:0021766	hippocampus development	Zbtb18	IMP	MGI:MGI:3851929	Mouse	PMID:19409883
Biological Process	GO:0048872	homeostasis of number of cells	Zbtb18	IMP	MGI:MGI:3851929	Mouse	PMID:19409883
Biological Process	GO:0001701	in utero embryonic development	Zbtb18	IMP	MGI:MGI:3851929	Mouse	PMID:19409883
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Zbtb18	IDA		Mouse	MGI:MGI:4418579|PMID:20059953
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ZBTB18	IDA		Human	PMID:9756912
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Zbtb18	IDA		Mouse	MGI:MGI:4418579|PMID:20059953
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Zbtb18	IDA		Mouse	PMID:18262495
Biological Process	GO:0048666	neuron development	Zbtb18	IMP	MGI:MGI:3851929	Mouse	PMID:19409883
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ZBTB18	IDA		Human	PMID:25796446
Biological Process	GO:0051302	regulation of cell division	Zbtb18	IMP	MGI:MGI:3851929	Mouse	PMID:19409883
Biological Process	GO:0007519	skeletal muscle tissue development	Zbtb18	IMP		Mouse	MGI:MGI:4418579|PMID:20059953

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern