Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes XRCC2
  • Mouse genes Xrcc2
  • Rat genes Xrcc2
  • Zfish genes xrcc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Xrcc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000400	four-way junction DNA binding	XRCC2	IDA		Human	PMID:20207730
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O75771	Human	PMID:10749867
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O75771	Human	PMID:10871607
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O75771	Human	PMID:11751635
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O43502	Human	PMID:11842113
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O75771	Human	PMID:11842113
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O75771	Human	PMID:12975363
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O75771	Human	PMID:16710300
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O43502	Human	PMID:24141787
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O75771	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O75771	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O43502	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O75771	Human	PMID:28864920
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O75771	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O75771	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XRCC2	IPI	UniProtKB:O75771	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	Xrcc2	IPI	PR:Q9EP87	Mouse	PMID:19327148
Molecular Function	GO:0005515	protein binding	Xrcc2	IPI	PR:O55230	Mouse	PMID:20813759
Molecular Function	GO:0005515	protein binding	Xrcc2	IPI	PR:O55230-1	Mouse	PMID:19327148
Cellular Component	GO:0005813	centrosome	XRCC2	IDA		Human	PMID:21276791
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	XRCC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	XRCC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex	XRCC2	IDA		Human	PMID:11751635
Cellular Component	GO:0005657	replication fork	XRCC2	IDA		Human	PMID:20207730
Biological Process	GO:0007098	centrosome cycle	XRCC2	IMP		Human	PMID:21276791
Biological Process	GO:0006974	DNA damage response	Xrcc2	IMP	MGI:MGI:2662686	Mouse	PMID:15979950
Biological Process	GO:0006974	DNA damage response	Xrcc2	IMP	MGI:MGI:3654106	Mouse	PMID:16777961
Biological Process	GO:0006281	DNA repair	XRCC2	IGI		Human	PMID:10422536
Biological Process	GO:0000724	double-strand break repair via homologous recombination	XRCC2	IMP		Human	PMID:23149936
Biological Process	GO:0000724	double-strand break repair via homologous recombination	Xrcc2	IMP	MGI:MGI:3654106	Mouse	PMID:16777961
Biological Process	GO:0001701	in utero embryonic development	Xrcc2	IMP	MGI:MGI:3654106	Mouse	PMID:16777961
Biological Process	GO:0000278	mitotic cell cycle	XRCC2	IMP		Human	PMID:21276791
Biological Process	GO:0035264	multicellular organism growth	Xrcc2	IGI	MGI:MGI:98834	Mouse	PMID:17116431
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Xrcc2	IGI	MGI:MGI:98834	Mouse	PMID:16777961
Biological Process	GO:0022008	neurogenesis	Xrcc2	IMP	MGI:MGI:3654106	Mouse	PMID:16777961
Biological Process	GO:0022008	neurogenesis	Xrcc2	IMP	MGI:MGI:2662686	Mouse	PMID:17116431
Biological Process	GO:0050769	positive regulation of neurogenesis	Xrcc2	IMP	MGI:MGI:3654106	Mouse	PMID:16777961
Biological Process	GO:2000269	regulation of fibroblast apoptotic process	Xrcc2	IGI	MGI:MGI:98834	Mouse	PMID:17116431
Biological Process	GO:0010332	response to gamma radiation	Xrcc2	IMP	MGI:MGI:3654106	Mouse	PMID:16777961
Biological Process	GO:0010165	response to X-ray	Xrcc2	IMP	MGI:MGI:2662686	Mouse	PMID:15979950
Biological Process	GO:0001756	somitogenesis	Xrcc2	IMP	MGI:MGI:1927345	Mouse	PMID:17116431
Biological Process	GO:0042148	strand invasion	XRCC2	IDA		Human	PMID:11834724

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern