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Gene Ontology Browser
Term Detail
GO term:centrosome cycle
GO id:GO:0007098
Definition:The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
Number of paths to term: 13

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-aorganelle organization
                                        is-acytoskeleton organization
                                                is-amicrotubule cytoskeleton organization
                                                        part-ofmicrotubule organizing center organization
                                                                is-acentrosome organization
                                                                        is-acentriole elongation +
                                                                        is-acentriole replication +
                                                                        is-acentriole-centriole cohesion +
                                                                        is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                                                                part-ofcentrosome duplication +
                                                                                part-ofcentrosome separation +
                                                                                is-amale meiosis centrosome cycle
                                                                                negatively-regulatesnegative regulation of centrosome cycle +
                                                                                positively-regulatespositive regulation of centrosome cycle +
                                                                                part-ofregulation of centriole-centriole cohesion +
                                                                                regulatesregulation of centrosome cycle +
                                                                        is-acentrosome duplication +
                                                                        is-acentrosome separation +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-aorganelle organization
                                        is-amicrotubule organizing center organization
                                                is-acentrosome organization
                                                        is-acentriole elongation +
                                                        is-acentriole replication +
                                                        is-acentriole-centriole cohesion +
                                                        is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                                                part-ofcentrosome duplication +
                                                                part-ofcentrosome separation +
                                                                is-amale meiosis centrosome cycle
                                                                negatively-regulatesnegative regulation of centrosome cycle +
                                                                positively-regulatespositive regulation of centrosome cycle +
                                                                part-ofregulation of centriole-centriole cohesion +
                                                                regulatesregulation of centrosome cycle +
                                                        is-acentrosome duplication +
                                                        is-acentrosome separation +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-aorganelle organization
                                        is-asingle-organism organelle organization
                                                is-amicrotubule cytoskeleton organization
                                                        part-ofmicrotubule organizing center organization
                                                                is-acentrosome organization
                                                                        is-acentriole elongation +
                                                                        is-acentriole replication +
                                                                        is-acentriole-centriole cohesion +
                                                                        is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                                                                part-ofcentrosome duplication +
                                                                                part-ofcentrosome separation +
                                                                                is-amale meiosis centrosome cycle
                                                                                negatively-regulatesnegative regulation of centrosome cycle +
                                                                                positively-regulatespositive regulation of centrosome cycle +
                                                                                part-ofregulation of centriole-centriole cohesion +
                                                                                regulatesregulation of centrosome cycle +
                                                                        is-acentrosome duplication +
                                                                        is-acentrosome separation +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acell cycle process
                                is-aactin filament reorganization involved in cell cycle
                                is-aactomyosin contractile ring assembly actin filament organization +
                                is-aattachment of spindle microtubules to kinetochore +
                                is-acell cycle arrest +
                                is-acell cycle checkpoint +
                                is-acell cycle DNA replication +
                                is-acell cycle DNA replication DNA ligation +
                                is-acell cycle DNA replication DNA unwinding +
                                is-acell cycle DNA replication initiation +
                                is-acell cycle DNA replication maintenance of fidelity +
                                is-acell cycle DNA replication termination +
                                is-acell cycle phase transition +
                                is-acell cycle switching +
                                is-acentriole elongation +
                                is-acentriole replication +
                                is-acentromere separation +
                                is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                        part-ofcentrosome duplication +
                                        part-ofcentrosome separation +
                                        is-amale meiosis centrosome cycle
                                        negatively-regulatesnegative regulation of centrosome cycle +
                                        positively-regulatespositive regulation of centrosome cycle +
                                        part-ofregulation of centriole-centriole cohesion +
                                        regulatesregulation of centrosome cycle +
                                is-acentrosome duplication +
                                is-acentrosome separation +
                                is-achromosome attachment to the nuclear envelope +
                                is-achromosome movement towards spindle pole +
                                is-achromosome separation +
                                is-acytokinesis +
                                is-acytokinetic process +
                                is-adetection of DNA damage stimulus involved in DNA damage checkpoint +
                                is-adetection of stimulus involved in DNA replication checkpoint +
                                is-aDNA replication preinitiation complex assembly +
                                is-aDNA strand elongation involved in cell cycle DNA replication +
                                is-aestablishment of sister chromatid cohesion +
                                is-aG0 to G1 transition +
                                is-aG1 to G0 transition +
                                is-amaintenance of protein location to spindle pole body
                                is-amaintenance of sister chromatid cohesion +
                                is-ameiotic cell cycle process +
                                is-amicrotubule anchoring at spindle pole body +
                                is-amitotic cell cycle process +
                                is-amyosin filament organization involved in cytokinetic actomyosin contractile ring assembly
                                negatively-regulatesnegative regulation of cell cycle process +
                                is-anuclear chromosome segregation +
                                positively-regulatespositive regulation of cell cycle process +
                                is-apre-replicative complex assembly involved in cell cycle DNA replication +
                                is-are-entry into mitotic cell cycle +
                                regulatesregulation of cell cycle process +
                                is-aregulation of syncytial blastoderm mitotic cell cycle +
                                is-asignal transduction involved in DNA damage checkpoint +
                                is-asister chromatid cohesion +
                                is-aspindle elongation +
                                is-aspindle localization +
                                is-aspindle midzone assembly +
                                is-aspindle organization +
                                is-aspindle pole body organization +
                                is-aspindle pole body separation +
                                is-asynthesis of RNA primer involved in cell cycle DNA replication +
                                is-atelomere maintenance via semi-conservative replication +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular component organization
                                is-aorganelle organization
                                        is-acytoskeleton organization
                                                is-amicrotubule cytoskeleton organization
                                                        part-ofmicrotubule organizing center organization
                                                                is-acentrosome organization
                                                                        is-acentriole elongation +
                                                                        is-acentriole replication +
                                                                        is-acentriole-centriole cohesion +
                                                                        is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                                                                part-ofcentrosome duplication +
                                                                                part-ofcentrosome separation +
                                                                                is-amale meiosis centrosome cycle
                                                                                negatively-regulatesnegative regulation of centrosome cycle +
                                                                                positively-regulatespositive regulation of centrosome cycle +
                                                                                part-ofregulation of centriole-centriole cohesion +
                                                                                regulatesregulation of centrosome cycle +
                                                                        is-acentrosome duplication +
                                                                        is-acentrosome separation +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular component organization
                                is-aorganelle organization
                                        is-amicrotubule organizing center organization
                                                is-acentrosome organization
                                                        is-acentriole elongation +
                                                        is-acentriole replication +
                                                        is-acentriole-centriole cohesion +
                                                        is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                                                part-ofcentrosome duplication +
                                                                part-ofcentrosome separation +
                                                                is-amale meiosis centrosome cycle
                                                                negatively-regulatesnegative regulation of centrosome cycle +
                                                                positively-regulatespositive regulation of centrosome cycle +
                                                                part-ofregulation of centriole-centriole cohesion +
                                                                regulatesregulation of centrosome cycle +
                                                        is-acentrosome duplication +
                                                        is-acentrosome separation +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular component organization
                                is-aorganelle organization
                                        is-asingle-organism organelle organization
                                                is-amicrotubule cytoskeleton organization
                                                        part-ofmicrotubule organizing center organization
                                                                is-acentrosome organization
                                                                        is-acentriole elongation +
                                                                        is-acentriole replication +
                                                                        is-acentriole-centriole cohesion +
                                                                        is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                                                                part-ofcentrosome duplication +
                                                                                part-ofcentrosome separation +
                                                                                is-amale meiosis centrosome cycle
                                                                                negatively-regulatesnegative regulation of centrosome cycle +
                                                                                positively-regulatespositive regulation of centrosome cycle +
                                                                                part-ofregulation of centriole-centriole cohesion +
                                                                                regulatesregulation of centrosome cycle +
                                                                        is-acentrosome duplication +
                                                                        is-acentrosome separation +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-aactin filament reorganization involved in cell cycle
                                                is-aactomyosin contractile ring assembly actin filament organization +
                                                is-aattachment of spindle microtubules to kinetochore +
                                                is-acell cycle arrest +
                                                is-acell cycle checkpoint +
                                                is-acell cycle DNA replication +
                                                is-acell cycle DNA replication DNA ligation +
                                                is-acell cycle DNA replication DNA unwinding +
                                                is-acell cycle DNA replication initiation +
                                                is-acell cycle DNA replication maintenance of fidelity +
                                                is-acell cycle DNA replication termination +
                                                is-acell cycle phase transition +
                                                is-acell cycle switching +
                                                is-acentriole elongation +
                                                is-acentriole replication +
                                                is-acentromere separation +
                                                is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                                        part-ofcentrosome duplication +
                                                        part-ofcentrosome separation +
                                                        is-amale meiosis centrosome cycle
                                                        negatively-regulatesnegative regulation of centrosome cycle +
                                                        positively-regulatespositive regulation of centrosome cycle +
                                                        part-ofregulation of centriole-centriole cohesion +
                                                        regulatesregulation of centrosome cycle +
                                                is-acentrosome duplication +
                                                is-acentrosome separation +
                                                is-achromosome attachment to the nuclear envelope +
                                                is-achromosome movement towards spindle pole +
                                                is-achromosome separation +
                                                is-acytokinesis +
                                                is-acytokinetic process +
                                                is-adetection of DNA damage stimulus involved in DNA damage checkpoint +
                                                is-adetection of stimulus involved in DNA replication checkpoint +
                                                is-aDNA replication preinitiation complex assembly +
                                                is-aDNA strand elongation involved in cell cycle DNA replication +
                                                is-aestablishment of sister chromatid cohesion +
                                                is-aG0 to G1 transition +
                                                is-aG1 to G0 transition +
                                                is-amaintenance of protein location to spindle pole body
                                                is-amaintenance of sister chromatid cohesion +
                                                is-ameiotic cell cycle process +
                                                is-amicrotubule anchoring at spindle pole body +
                                                is-amitotic cell cycle process +
                                                is-amyosin filament organization involved in cytokinetic actomyosin contractile ring assembly
                                                negatively-regulatesnegative regulation of cell cycle process +
                                                is-anuclear chromosome segregation +
                                                positively-regulatespositive regulation of cell cycle process +
                                                is-apre-replicative complex assembly involved in cell cycle DNA replication +
                                                is-are-entry into mitotic cell cycle +
                                                regulatesregulation of cell cycle process +
                                                is-aregulation of syncytial blastoderm mitotic cell cycle +
                                                is-asignal transduction involved in DNA damage checkpoint +
                                                is-asister chromatid cohesion +
                                                is-aspindle elongation +
                                                is-aspindle localization +
                                                is-aspindle midzone assembly +
                                                is-aspindle organization +
                                                is-aspindle pole body organization +
                                                is-aspindle pole body separation +
                                                is-asynthesis of RNA primer involved in cell cycle DNA replication +
                                                is-atelomere maintenance via semi-conservative replication +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-amicrotubule-based process
                                        is-amicrotubule cytoskeleton organization
                                                part-ofmicrotubule organizing center organization
                                                        is-acentrosome organization
                                                                is-acentriole elongation +
                                                                is-acentriole replication +
                                                                is-acentriole-centriole cohesion +
                                                                is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                                                        part-ofcentrosome duplication +
                                                                        part-ofcentrosome separation +
                                                                        is-amale meiosis centrosome cycle
                                                                        negatively-regulatesnegative regulation of centrosome cycle +
                                                                        positively-regulatespositive regulation of centrosome cycle +
                                                                        part-ofregulation of centriole-centriole cohesion +
                                                                        regulatesregulation of centrosome cycle +
                                                                is-acentrosome duplication +
                                                                is-acentrosome separation +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-asingle-organism organelle organization
                                        is-amicrotubule cytoskeleton organization
                                                part-ofmicrotubule organizing center organization
                                                        is-acentrosome organization
                                                                is-acentriole elongation +
                                                                is-acentriole replication +
                                                                is-acentriole-centriole cohesion +
                                                                is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                                                        part-ofcentrosome duplication +
                                                                        part-ofcentrosome separation +
                                                                        is-amale meiosis centrosome cycle
                                                                        negatively-regulatesnegative regulation of centrosome cycle +
                                                                        positively-regulatespositive regulation of centrosome cycle +
                                                                        part-ofregulation of centriole-centriole cohesion +
                                                                        regulatesregulation of centrosome cycle +
                                                                is-acentrosome duplication +
                                                                is-acentrosome separation +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-aactin filament reorganization involved in cell cycle
                                                is-aactomyosin contractile ring assembly actin filament organization +
                                                is-aattachment of spindle microtubules to kinetochore +
                                                is-acell cycle arrest +
                                                is-acell cycle checkpoint +
                                                is-acell cycle DNA replication +
                                                is-acell cycle DNA replication DNA ligation +
                                                is-acell cycle DNA replication DNA unwinding +
                                                is-acell cycle DNA replication initiation +
                                                is-acell cycle DNA replication maintenance of fidelity +
                                                is-acell cycle DNA replication termination +
                                                is-acell cycle phase transition +
                                                is-acell cycle switching +
                                                is-acentriole elongation +
                                                is-acentriole replication +
                                                is-acentromere separation +
                                                is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                                        part-ofcentrosome duplication +
                                                        part-ofcentrosome separation +
                                                        is-amale meiosis centrosome cycle
                                                        negatively-regulatesnegative regulation of centrosome cycle +
                                                        positively-regulatespositive regulation of centrosome cycle +
                                                        part-ofregulation of centriole-centriole cohesion +
                                                        regulatesregulation of centrosome cycle +
                                                is-acentrosome duplication +
                                                is-acentrosome separation +
                                                is-achromosome attachment to the nuclear envelope +
                                                is-achromosome movement towards spindle pole +
                                                is-achromosome separation +
                                                is-acytokinesis +
                                                is-acytokinetic process +
                                                is-adetection of DNA damage stimulus involved in DNA damage checkpoint +
                                                is-adetection of stimulus involved in DNA replication checkpoint +
                                                is-aDNA replication preinitiation complex assembly +
                                                is-aDNA strand elongation involved in cell cycle DNA replication +
                                                is-aestablishment of sister chromatid cohesion +
                                                is-aG0 to G1 transition +
                                                is-aG1 to G0 transition +
                                                is-amaintenance of protein location to spindle pole body
                                                is-amaintenance of sister chromatid cohesion +
                                                is-ameiotic cell cycle process +
                                                is-amicrotubule anchoring at spindle pole body +
                                                is-amitotic cell cycle process +
                                                is-amyosin filament organization involved in cytokinetic actomyosin contractile ring assembly
                                                negatively-regulatesnegative regulation of cell cycle process +
                                                is-anuclear chromosome segregation +
                                                positively-regulatespositive regulation of cell cycle process +
                                                is-apre-replicative complex assembly involved in cell cycle DNA replication +
                                                is-are-entry into mitotic cell cycle +
                                                regulatesregulation of cell cycle process +
                                                is-aregulation of syncytial blastoderm mitotic cell cycle +
                                                is-asignal transduction involved in DNA damage checkpoint +
                                                is-asister chromatid cohesion +
                                                is-aspindle elongation +
                                                is-aspindle localization +
                                                is-aspindle midzone assembly +
                                                is-aspindle organization +
                                                is-aspindle pole body organization +
                                                is-aspindle pole body separation +
                                                is-asynthesis of RNA primer involved in cell cycle DNA replication +
                                                is-atelomere maintenance via semi-conservative replication +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-amicrotubule-based process
                                        is-amicrotubule cytoskeleton organization
                                                part-ofmicrotubule organizing center organization
                                                        is-acentrosome organization
                                                                is-acentriole elongation +
                                                                is-acentriole replication +
                                                                is-acentriole-centriole cohesion +
                                                                is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                                                        part-ofcentrosome duplication +
                                                                        part-ofcentrosome separation +
                                                                        is-amale meiosis centrosome cycle
                                                                        negatively-regulatesnegative regulation of centrosome cycle +
                                                                        positively-regulatespositive regulation of centrosome cycle +
                                                                        part-ofregulation of centriole-centriole cohesion +
                                                                        regulatesregulation of centrosome cycle +
                                                                is-acentrosome duplication +
                                                                is-acentrosome separation +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-asingle-organism organelle organization
                                        is-amicrotubule cytoskeleton organization
                                                part-ofmicrotubule organizing center organization
                                                        is-acentrosome organization
                                                                is-acentriole elongation +
                                                                is-acentriole replication +
                                                                is-acentriole-centriole cohesion +
                                                                is-acentrosome cycle [GO:0007098] (75 genes, 111 annotations)
                                                                        part-ofcentrosome duplication +
                                                                        part-ofcentrosome separation +
                                                                        is-amale meiosis centrosome cycle
                                                                        negatively-regulatesnegative regulation of centrosome cycle +
                                                                        positively-regulatespositive regulation of centrosome cycle +
                                                                        part-ofregulation of centriole-centriole cohesion +
                                                                        regulatesregulation of centrosome cycle +
                                                                is-acentrosome duplication +
                                                                is-acentrosome separation +


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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory