Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes XK
  • Mouse genes Xk
  • Rat genes Xk
  • Zfish genes xk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Xk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	XK	IPI	UniProtKB:P23276	Human	PMID:7737196
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	XK	IMP		Human	PMID:32845802
Cellular Component	GO:0005789	endoplasmic reticulum membrane	XK	IDA		Human	PMID:32845802
Cellular Component	GO:0005886	plasma membrane	XK	IDA		Human	PMID:32845802
Cellular Component	GO:0005886	plasma membrane	XK	IDA		Human	PMID:9593744
Cellular Component	GO:0005886	plasma membrane	Xk	IDA		Mouse	MGI:MGI:6716960|PMID:25231987
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Xk	IGI	MGI:MGI:95285	Mouse	PMID:23122227
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Xk	IGI	MGI:MGI:1346053	Mouse	PMID:23122227
Biological Process	GO:0010961	intracellular magnesium ion homeostasis	Xk	IGI	MGI:MGI:95285	Mouse	PMID:23122227
Biological Process	GO:0010961	intracellular magnesium ion homeostasis	Xk	IGI	MGI:MGI:1346053	Mouse	PMID:23122227
Biological Process	GO:0042552	myelination	Xk	IMP	MGI:MGI:5581658	Mouse	PMID:24405768
Biological Process	GO:0031133	regulation of axon diameter	Xk	IGI	MGI:MGI:1346053	Mouse	PMID:24405768
Biological Process	GO:0008361	regulation of cell size	Xk	IGI	MGI:MGI:1346053	Mouse	PMID:23122227
Biological Process	GO:0048741	skeletal muscle fiber development	Xk	IGI	MGI:MGI:1346053	Mouse	PMID:24405768

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern