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Xk
Gene Detail
Symbol

Name
ID
Xk
Kell blood group precursor (McLeod phenotype) homolog
MGI:103569
Synonyms
1810038K19Rik, Xk
Feature Type
protein coding gene
Genetic Map
Chromosome X
4.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
ChrX:9272756-9313250 bp, + strand
From VEGA annotation of GRCm38

  40495 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36393  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: XK
Gene Tree: Xk

Human
homologs
XK, X-linked Kx blood group
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 7504
neXtProt AC: NX_P51811

Human Synonyms: KX, MCLDS, NA, NAC, X1k, XKR1

Human Chr (Location): Xp21.1; chrX:37685781-37732130 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human XK

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from CvDC )
Interactions
Xk interacts with 373 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process amino acid transport, cellular calcium ion homeostasis, ...
Component cell, integral component of membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (20)    Tissues (1)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 20
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase xk    NEW 
Molecular
reagents
All nucleic(15) Genomic(1) cDNA(13) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000016888 (Evidence)
Ensembl Gene Model ENSMUSG00000015342 (Evidence)
Entrez Gene 22439 (Evidence)
UniGene 56468
DFCI TC1716722, TC1622655, TC1586229
DoTS DT.99851373, DT.55158144, DT.55117663, DT.103560224
NIA Mouse Gene Index U040331
Consensus CDS Project CCDS30008.1
International Mouse Phenotyping Consortium Status Xk
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016888 VEGA Gene Model | MGI Sequence Detail 40495 C57BL/6J ±  kb
transcript OTTMUST00000040989 VEGA | MGI Sequence Detail 5076 Not Applicable 
polypeptide OTTMUSP00000018348 VEGA | MGI Sequence Detail 446 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(2)
Polymorphisms
RFLP(2) : SNPs within 2kb(177 from dbSNP Build 137)    SNPs within 2kb including multiple locations(259)
Protein-related
information
ResourceIDDescription
InterPro IPR018629 Transport protein XK
Protein Ontology PR:000017481 membrane transport protein XK
References
(Earliest) J:26635 Blair HJ, et al., High-resolution comparative mapping of the proximal region of the mouse X chromosome. Genomics. 1995 Jul 20;28(2):305-10
(Latest) J:206464 Zhu X, et al., Giant Axon Formation in Mice Lacking Kell, XK, or Kell and XK: Animal Models of McLeod Neuroacanthocytosis Syndrome. Am J Pathol. 2014 Mar;184(3):800-7
All references(32)
Other
accession IDs
MGD-MRK-24454, MGI:1916432

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory