Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WTIP
  • Mouse genes Wtip
  • Rat genes Wtip
  • Zfish genes wtip
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wtip

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:O95835	Human	PMID:20303269
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:Q9H4B6	Human	PMID:20303269
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:Q9NRM7	Human	PMID:20303269
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:P06730	Human	PMID:20616046
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:P26196	Human	PMID:20616046
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:Q8IU60	Human	PMID:20616046
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:Q9UKV8	Human	PMID:20616046
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:Q9UL18	Human	PMID:20616046
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:P40337	Human	PMID:22286099
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:Q96KS0	Human	PMID:22286099
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:Q9H6Z9	Human	PMID:22286099
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:Q9H9G7	Human	PMID:28683311
Molecular Function	GO:0005515	protein binding	WTIP	IPI	UniProtKB:Q14160	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	Wtip	IPI	UniProtKB:P19382|UniProtKB:P97469|UniProtKB:Q02085|UniProtKB:Q99M85	Mouse	MGI:MGI:5318024|PMID:18331720
Molecular Function	GO:0003714	transcription corepressor activity	Wtip	IDA		Mouse	MGI:MGI:3773767|PMID:17909014
Cellular Component	GO:0036064	ciliary basal body	wtip	IDA		Zfish	PMID:27484451
Cellular Component	GO:0036064	ciliary basal body	wtip	IDA		Zfish	PMID:23213452
Cellular Component	GO:0000932	P-body	WTIP	IDA		Human	PMID:20616046
Biological Process	GO:0060271	cilium assembly	wtip	IMP	ZFIN:ZDB-MRPHLNO-130117-3	Zfish	PMID:23213452
Biological Process	GO:0035844	cloaca development	wtip	IGI	ZFIN:ZDB-MRPHLNO-110614-5,ZFIN:ZDB-MRPHLNO-130117-3	Zfish	PMID:23213452
Biological Process	GO:0035844	cloaca development	wtip	IMP	ZFIN:ZDB-MRPHLNO-130117-3	Zfish	PMID:23213452
Biological Process	GO:0035844	cloaca development	wtip	IMP	ZFIN:ZDB-MRPHLNO-130118-1	Zfish	PMID:23213452
Biological Process	GO:0007010	cytoskeleton organization	WTIP	IMP		Human	PMID:21834987
Biological Process	GO:0061371	determination of heart left/right asymmetry	wtip	IMP	ZFIN:ZDB-MRPHLNO-130117-3	Zfish	PMID:27484451
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	wtip	IMP	ZFIN:ZDB-MRPHLNO-130117-3	Zfish	PMID:27484451
Biological Process	GO:0000132	establishment of mitotic spindle orientation	wtip	IMP	ZFIN:ZDB-MRPHLNO-130117-3	Zfish	PMID:23213452
Biological Process	GO:0000132	establishment of mitotic spindle orientation	wtip	IGI	ZFIN:ZDB-MRPHLNO-110614-5,ZFIN:ZDB-MRPHLNO-130117-3	Zfish	PMID:23213452
Biological Process	GO:0001947	heart looping	wtip	IMP	ZFIN:ZDB-MRPHLNO-130117-3	Zfish	PMID:27484451
Biological Process	GO:0035195	miRNA-mediated gene silencing	WTIP	IMP		Human	PMID:20616046
Biological Process	GO:0035331	negative regulation of hippo signaling	WTIP	IDA		Human	PMID:20303269
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	WTIP	IMP		Human	PMID:20616046
Biological Process	GO:0022604	regulation of cell morphogenesis	WTIP	IMP		Human	PMID:21834987
Biological Process	GO:0001666	response to hypoxia	WTIP	IDA		Human	PMID:22286099
Biological Process	GO:0061032	visceral serous pericardium development	wtip	IMP	ZFIN:ZDB-MRPHLNO-130117-3	Zfish	PMID:27484451
Biological Process	GO:0061032	visceral serous pericardium development	wtip	IGI	ZFIN:ZDB-GENE-980526-558	Zfish	PMID:27484451

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern