Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WIZ
  • Mouse genes Wiz
  • Rat genes Wiz
  • Zfish genes wiza,wizb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wiz

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	WIZ	IDA		Human	PMID:25789554
Molecular Function	GO:1990226	histone methyltransferase binding	WIZ	IPI	UniProtKB:Q96KQ7|UniProtKB:Q9H9B1	Human	PMID:16702210
Molecular Function	GO:1990226	histone methyltransferase binding	Wiz	IPI	UniProtKB:Q5DW34|UniProtKB:Q9Z148	Mouse	MGI:MGI:3690291|PMID:16702210
Molecular Function	GO:0005515	protein binding	WIZ	IPI	UniProtKB:P56545	Human	PMID:16702210
Molecular Function	GO:0005515	protein binding	WIZ	IPI	UniProtKB:Q13363	Human	PMID:16702210
Molecular Function	GO:0005515	protein binding	Wiz	IPI	UniProtKB:O88712|UniProtKB:P56546	Mouse	MGI:MGI:3690291|PMID:16702210
Molecular Function	GO:0044877	protein-containing complex binding	WIZ	IDA		Human	PMID:16702210
Molecular Function	GO:0044877	protein-containing complex binding	Wiz	IDA		Mouse	MGI:MGI:3690291|PMID:16702210
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	WIZ	IDA		Human	PMID:25789554
Molecular Function	GO:0070984	SET domain binding	Wiz	IPI	UniProtKB:Q5DW34|UniProtKB:Q96KQ7|UniProtKB:Q9Z148	Mouse	MGI:MGI:3690291|PMID:16702210
Molecular Function	GO:0001222	transcription corepressor binding	WIZ	IPI	UniProtKB:Q96JN0	Human	PMID:29628311
Cellular Component	GO:0070062	extracellular exosome	WIZ	HDA		Human	PMID:19056867
Cellular Component	GO:0030496	midbody	WIZ	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	WIZ	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	WIZ	IDA		Human	PMID:16702210
Cellular Component	GO:0005634	nucleus	Wiz	IDA		Mouse	MGI:MGI:3690291|PMID:16702210
Biological Process	GO:0010571	positive regulation of nuclear cell cycle DNA replication	WIZ	IMP		Human	PMID:23545495
Biological Process	GO:0050821	protein stabilization	WIZ	IMP		Human	PMID:16702210

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern