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Wiz Gene Detail
Summary
  • Symbol
    Wiz
  • Name
    widely-interspaced zinc finger motifs
  • Feature Type
    protein coding gene
  • IDs
    MGI:1332638
    NCBI Gene: 22404
Location & Maps
more
  • Sequence Map
    Chr17:32354055-32389401 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      35347 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 17.52 cM, cytoband B2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    WIZ, widely interspaced zinc finger motifs
  • Vertebrate Orthologs
    8
  • Human Ortholog
    WIZ, widely interspaced zinc finger motifs
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ZNF803
  • Links
    NCBI Gene ID: 58525
    neXtProt AC: NX_O95785

  • Chr Location
    19p13.1; chr19:15421507-15449956 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    16
  • Chemically induced (ENU)
    1
  • Gene trapped
    13
  • Targeted
    2
  • Incidental Mutations
Homozygous mutant mice die prenatally.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035221 VEGA Gene Model | MGI Sequence Detail 35347 C57BL/6J ±  kb
transcript OTTMUST00000089754 VEGA | MGI Sequence Detail 3296 Not Applicable  
polypeptide OTTMUSP00000049081 VEGA | MGI Sequence Detail 973 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    97 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 122
    cDNA 118
    Primer pair 3
    Other 1

    Microarray probesets 4
References
more
  • Summaries
    All 34
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:50534 Funke B, et al., Isolation and characterization of a human gene containing a nuclear localization signal from the critical region for velo-cardio-facial syndrome on 22q11. Genomics. 1998 Oct 15;53(2):146-54
  • Latest
    J:201508 Daxinger L, et al., An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse. Genome Biol. 2013 Sep 11;14(9):R96

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory