Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WFIKKN2
  • Mouse genes Wfikkn2
  • Rat genes Wfikkn2
  • Zfish genes wfikkn2a,wfikkn2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wfikkn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	WFIKKN2	IPI	UniProtKB:O95390	Human	PMID:18596030
Molecular Function	GO:0005515	protein binding	Wfikkn2	IPI	PR:O08689	Mouse	PMID:12595574
Molecular Function	GO:0005515	protein binding	Wfikkn2	IPI	UniProtKB:O95390	Mouse	PMID:24019467
Molecular Function	GO:0048019	receptor antagonist activity	WFIKKN2	IDA		Human	PMID:21054789
Molecular Function	GO:0050431	transforming growth factor beta binding	WFIKKN2	IPI	UniProtKB:O14793	Human	PMID:12595574
Molecular Function	GO:0050431	transforming growth factor beta binding	WFIKKN2	IDA		Human	PMID:21054789
Cellular Component	GO:0005576	extracellular region	Wfikkn2	IDA		Mouse	PMID:24019467
Cellular Component	GO:0005615	extracellular space	WFIKKN2	IDA		Human	PMID:12595574
Cellular Component	GO:0005615	extracellular space	Wfikkn2	IDA		Mouse	MGI:MGI:2676508|PMID:12595574
Biological Process	GO:0055001	muscle cell development	Wfikkn2	IMP	MGI:MGI:5546173	Mouse	PMID:24019467
Biological Process	GO:0043392	negative regulation of DNA binding	Wfikkn2	IDA		Mouse	PMID:24019467
Biological Process	GO:0032091	negative regulation of protein binding	Wfikkn2	IDA		Mouse	PMID:24019467
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	WFIKKN2	IDA		Human	PMID:21054789
Biological Process	GO:0060021	roof of mouth development	Wfikkn2	IGI	MGI:MGI:1338027	Mouse	PMID:24019467
Biological Process	GO:0001501	skeletal system development	Wfikkn2	IGI	MGI:MGI:1338027	Mouse	PMID:24019467
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Wfikkn2	IDA		Mouse	PMID:12595574

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern