Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WDR81
  • Mouse genes Wdr81
  • Rat genes Wdr81
  • Zfish genes wdr81
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wdr81

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	WDR81	IDA		Human	PMID:28404643
Molecular Function	GO:0035014	phosphatidylinositol 3-kinase regulator activity	WDR81	IMP		Human	PMID:26783301
Molecular Function	GO:0005515	protein binding	WDR81	IPI	UniProtKB:A4D1P6	Human	PMID:26783301
Molecular Function	GO:0005515	protein binding	WDR81	IPI	UniProtKB:A4D1P6	Human	PMID:27126989
Molecular Function	GO:0005515	protein binding	WDR81	IPI	UniProtKB:Q13501	Human	PMID:28404643
Molecular Function	GO:0005515	protein binding	WDR81	IPI	UniProtKB:Q9BXW4	Human	PMID:28404643
Cellular Component	GO:0000421	autophagosome membrane	WDR81	IDA		Human	PMID:28404643
Cellular Component	GO:0005829	cytosol	WDR81	IDA		Human	PMID:26783301
Cellular Component	GO:0005829	cytosol	WDR81	IDA		Human	PMID:27126989
Cellular Component	GO:0031901	early endosome membrane	WDR81	IDA		Human	PMID:26783301
Cellular Component	GO:0031901	early endosome membrane	WDR81	IDA		Human	PMID:27126989
Cellular Component	GO:0031313	extrinsic component of endosome membrane	WDR81	IDA		Human	PMID:26783301
Cellular Component	GO:0031313	extrinsic component of endosome membrane	WDR81	IDA		Human	PMID:27126989
Cellular Component	GO:0031902	late endosome membrane	WDR81	IDA		Human	PMID:26783301
Cellular Component	GO:0031902	late endosome membrane	WDR81	IDA		Human	PMID:27126989
Cellular Component	GO:0031902	late endosome membrane	WDR81	IDA		Human	PMID:28404643
Cellular Component	GO:0005765	lysosomal membrane	WDR81	IDA		Human	PMID:27126989
Cellular Component	GO:0005739	mitochondrion	WDR81	IDA		Human	PMID:28404643
Cellular Component	GO:0005739	mitochondrion	Wdr81	IDA		Mouse	MGI:MGI:5488990|PMID:23595742
Biological Process	GO:0035973	aggrephagy	WDR81	IMP		Human	PMID:28404643
Biological Process	GO:0045022	early endosome to late endosome transport	WDR81	IMP		Human	PMID:26783301
Biological Process	GO:0045022	early endosome to late endosome transport	WDR81	IMP		Human	PMID:27126989
Biological Process	GO:0007005	mitochondrion organization	Wdr81	IMP		Mouse	MGI:MGI:5488990|PMID:23595742
Biological Process	GO:0050821	protein stabilization	WDR81	IMP		Human	PMID:26783301
Biological Process	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	WDR81	IMP		Human	PMID:26783301
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	WDR81	IMP		Human	PMID:28404643

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern