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Gene Ontology Browser
Term Detail
GO term:regulation of phosphatidylinositol 3-kinase activity
Synonym: regulation of phosphoinositide 3-kinase activity
GO id:GO:0043551
Definition:Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring.
Number of paths to term: 26

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of kinase activity
                                                                                is-aregulation of lipid kinase activity
                                                                                        is-anegative regulation of lipid kinase activity +
                                                                                        is-apositive regulation of lipid kinase activity +
                                                                                        is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                        is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                        is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                                is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                                is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-aregulation of transferase activity
                                                        is-aregulation of kinase activity
                                                                is-aregulation of lipid kinase activity
                                                                        is-anegative regulation of lipid kinase activity +
                                                                        is-apositive regulation of lipid kinase activity +
                                                                        is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                        is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                        is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of kinase activity
                                                                                is-aregulation of lipid kinase activity
                                                                                        is-anegative regulation of lipid kinase activity +
                                                                                        is-apositive regulation of lipid kinase activity +
                                                                                        is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                        is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                        is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                                is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                                is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of primary metabolic process
                                                is-aregulation of lipid metabolic process
                                                        is-aregulation of lipid kinase activity
                                                                is-anegative regulation of lipid kinase activity +
                                                                is-apositive regulation of lipid kinase activity +
                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of molecular function
                                is-aregulation of catalytic activity
                                        is-aregulation of transferase activity
                                                is-aregulation of kinase activity
                                                        is-aregulation of lipid kinase activity
                                                                is-anegative regulation of lipid kinase activity +
                                                                is-apositive regulation of lipid kinase activity +
                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        is-aphosphate-containing compound metabolic process
                                                is-aphosphorylation
                                                        regulatesregulation of phosphorylation
                                                                is-aregulation of kinase activity
                                                                        is-aregulation of lipid kinase activity
                                                                                is-anegative regulation of lipid kinase activity +
                                                                                is-apositive regulation of lipid kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        is-aphosphate-containing compound metabolic process
                                                regulatesregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of kinase activity
                                                                        is-aregulation of lipid kinase activity
                                                                                is-anegative regulation of lipid kinase activity +
                                                                                is-apositive regulation of lipid kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        regulatesregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of kinase activity
                                                                        is-aregulation of lipid kinase activity
                                                                                is-anegative regulation of lipid kinase activity +
                                                                                is-apositive regulation of lipid kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                regulatesregulation of cellular metabolic process
                                        is-aregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of kinase activity
                                                                        is-aregulation of lipid kinase activity
                                                                                is-anegative regulation of lipid kinase activity +
                                                                                is-apositive regulation of lipid kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cellular metabolic process
                                        is-aregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of kinase activity
                                                                        is-aregulation of lipid kinase activity
                                                                                is-anegative regulation of lipid kinase activity +
                                                                                is-apositive regulation of lipid kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        is-aphosphate-containing compound metabolic process
                                                is-aphosphorylation
                                                        regulatesregulation of phosphorylation
                                                                is-aregulation of kinase activity
                                                                        is-aregulation of lipid kinase activity
                                                                                is-anegative regulation of lipid kinase activity +
                                                                                is-apositive regulation of lipid kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        is-aphosphate-containing compound metabolic process
                                                regulatesregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of kinase activity
                                                                        is-aregulation of lipid kinase activity
                                                                                is-anegative regulation of lipid kinase activity +
                                                                                is-apositive regulation of lipid kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        regulatesregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of kinase activity
                                                                        is-aregulation of lipid kinase activity
                                                                                is-anegative regulation of lipid kinase activity +
                                                                                is-apositive regulation of lipid kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                regulatesregulation of cellular metabolic process
                                        is-aregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of kinase activity
                                                                        is-aregulation of lipid kinase activity
                                                                                is-anegative regulation of lipid kinase activity +
                                                                                is-apositive regulation of lipid kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-alipid metabolic process
                                        regulatesregulation of lipid metabolic process
                                                is-aregulation of lipid kinase activity
                                                        is-anegative regulation of lipid kinase activity +
                                                        is-apositive regulation of lipid kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                        is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-alipid metabolic process
                                        regulatesregulation of lipid metabolic process
                                                is-aregulation of lipid kinase activity
                                                        is-anegative regulation of lipid kinase activity +
                                                        is-apositive regulation of lipid kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                        is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                regulatesregulation of primary metabolic process
                                        is-aregulation of lipid metabolic process
                                                is-aregulation of lipid kinase activity
                                                        is-anegative regulation of lipid kinase activity +
                                                        is-apositive regulation of lipid kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                        is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-aregulation of transferase activity
                                                is-aregulation of kinase activity
                                                        is-aregulation of lipid kinase activity
                                                                is-anegative regulation of lipid kinase activity +
                                                                is-apositive regulation of lipid kinase activity +
                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of cellular metabolic process
                                        is-aregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of kinase activity
                                                                        is-aregulation of lipid kinase activity
                                                                                is-anegative regulation of lipid kinase activity +
                                                                                is-apositive regulation of lipid kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of primary metabolic process
                                        is-aregulation of lipid metabolic process
                                                is-aregulation of lipid kinase activity
                                                        is-anegative regulation of lipid kinase activity +
                                                        is-apositive regulation of lipid kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                        is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-alipid metabolic process
                                        regulatesregulation of lipid metabolic process
                                                is-aregulation of lipid kinase activity
                                                        is-anegative regulation of lipid kinase activity +
                                                        is-apositive regulation of lipid kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                        is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-aregulation of cellular metabolic process
                                        is-aregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of kinase activity
                                                                        is-aregulation of lipid kinase activity
                                                                                is-anegative regulation of lipid kinase activity +
                                                                                is-apositive regulation of lipid kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of catalytic activity
                                        is-aregulation of transferase activity
                                                is-aregulation of kinase activity
                                                        is-aregulation of lipid kinase activity
                                                                is-anegative regulation of lipid kinase activity +
                                                                is-apositive regulation of lipid kinase activity +
                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of cellular metabolic process
                                        is-aregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of kinase activity
                                                                        is-aregulation of lipid kinase activity
                                                                                is-anegative regulation of lipid kinase activity +
                                                                                is-apositive regulation of lipid kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                                                is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                                                is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                                        is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                                        is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of primary metabolic process
                                        is-aregulation of lipid metabolic process
                                                is-aregulation of lipid kinase activity
                                                        is-anegative regulation of lipid kinase activity +
                                                        is-apositive regulation of lipid kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                        is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                is-apositive regulation of phosphatidylinositol 3-kinase activity


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-alipid metabolic process
                                        regulatesregulation of lipid metabolic process
                                                is-aregulation of lipid kinase activity
                                                        is-anegative regulation of lipid kinase activity +
                                                        is-apositive regulation of lipid kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol 4-kinase activity +
                                                        is-aregulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity +
                                                        is-aregulation of phosphatidylinositol 3-kinase activity [GO:0043551] (31 genes, 34 annotations)
                                                                is-anegative regulation of phosphatidylinositol 3-kinase activity
                                                                is-apositive regulation of phosphatidylinositol 3-kinase activity


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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory