Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WDR41
  • Mouse genes Wdr41
  • Rat genes Wdr41
  • Zfish genes wdr41
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wdr41

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	WDR41	IDA		Human	PMID:27103069
Molecular Function	GO:0005515	protein binding	WDR41	IPI	UniProtKB:Q8TEV9	Human	PMID:28195531
Molecular Function	GO:0005515	protein binding	WDR41	IPI	UniProtKB:Q8TEV9,UniProtKB:Q96LT7	Human	PMID:32303654
Cellular Component	GO:0005737	cytoplasm	WDR41	IDA		Human	PMID:27193190
Cellular Component	GO:0005737	cytoplasm	Wdr41	IDA		Mouse	MGI:MGI:5810480|PMID:27617292
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	WDR41	IPI		Human	PMID:29950492
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	WDR41	IDA		Human	PMID:27103069
Cellular Component	GO:0005765	lysosomal membrane	WDR41	HDA		Human	PMID:17897319
Biological Process	GO:0043547	positive regulation of GTPase activity	WDR41	IMP		Human	PMID:32303654
Biological Process	GO:0010506	regulation of autophagy	WDR41	IMP		Human	PMID:27103069

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern