Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WARS1
  • Mouse genes Wars1
  • Rat genes Wars1
  • Zfish genes wars1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wars1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019210	kinase inhibitor activity	WARS1	IDA		Human	PMID:22504299
Molecular Function	GO:0005515	protein binding	WARS1	IPI	UniProtKB:P04406	Human	PMID:15628863
Molecular Function	GO:0005515	protein binding	WARS1	IPI	UniProtKB:P33151	Human	PMID:20010843
Molecular Function	GO:0005515	protein binding	WARS1	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	WARS1	IPI	UniProtKB:P09874,UniProtKB:P78527	Human	PMID:22504299
Molecular Function	GO:0019904	protein domain specific binding	WARS1	IPI	UniProtKB:P09874	Human	PMID:22504299
Molecular Function	GO:0042803	protein homodimerization activity	WARS1	IDA		Human	PMID:22504299
Molecular Function	GO:0042803	protein homodimerization activity	WARS1	IDA		Human	PMID:28369220
Molecular Function	GO:0019901	protein kinase binding	WARS1	IPI	UniProtKB:P78527	Human	PMID:22504299
Molecular Function	GO:0004830	tryptophan-tRNA ligase activity	WARS1	IMP		Human	PMID:28369220
Molecular Function	GO:0004830	tryptophan-tRNA ligase activity	Wars1	IMP		Mouse	MGI:MGI:3055639|PMID:12060739
Molecular Function	GO:0004830	tryptophan-tRNA ligase activity	Wars1	IDA		Mouse	PMID:19941862
Cellular Component	GO:0005829	cytosol	WARS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	WARS1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	WARS1	HDA		Human	PMID:23533145
Cellular Component	GO:0005634	nucleus	WARS1	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	WARS1	IDA		Human	PMID:22504299
Cellular Component	GO:0032991	protein-containing complex	WARS1	IMP		Human	PMID:22504299
Biological Process	GO:0006469	negative regulation of protein kinase activity	WARS1	IDA		Human	PMID:22504299
Biological Process	GO:0010628	positive regulation of gene expression	WARS1	IDA		Human	PMID:22504299
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	WARS1	IMP		Human	PMID:22504299
Biological Process	GO:0045765	regulation of angiogenesis	WARS1	IDA		Human	PMID:11773625
Biological Process	GO:0045765	regulation of angiogenesis	WARS1	IDA		Human	PMID:11773626
Biological Process	GO:0006436	tryptophanyl-tRNA aminoacylation	Wars1	IDA		Mouse	MGI:MGI:3055639|PMID:12060739
Biological Process	GO:0006436	tryptophanyl-tRNA aminoacylation	Wars1	IDA		Mouse	PMID:19941862

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern